Cargando…

Comparison by Age of the Local Interferon Response to SARS-CoV-2 Suggests a Role for IFN-ε and -ω

Children generally develop a mild disease after SARS-CoV-2 infection whereas older adults are at risk of developing severe COVID-19. Recent transcriptomic analysis showed pre-activated innate immunity in children, resulting in a more effective anti-SARS-CoV-2 response upon infection. To further char...

Descripción completa

Detalles Bibliográficos
Autores principales:	Pierangeli, Alessandra, Gentile, Massimo, Oliveto, Giuseppe, Frasca, Federica, Sorrentino, Leonardo, Matera, Luigi, Nenna, Raffaella, Viscido, Agnese, Fracella, Matteo, Petrarca, Laura, D’Ettorre, Gabriella, Ceccarelli, Giancarlo, Midulla, Fabio, Antonelli, Guido, Scagnolari, Carolina
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9315386/ https://www.ncbi.nlm.nih.gov/pubmed/35903094 http://dx.doi.org/10.3389/fimmu.2022.873232

Ejemplares similares

The non-functional ACE2 isoform, but not the SARS-CoV-2 receptor, is induced as an interferon-stimulated gene, in SARS-CoV-2 infected adults
por: Oliveto, Giuseppe, et al.
Publicado: (2022)

Alterations in the Expression of IFN Lambda, IFN Gamma and Toll-like Receptors in Severe COVID-19 Patients
por: Sorrentino, Leonardo, et al.
Publicado: (2023)

ACE2 expression is related to the interferon response in airway epithelial cells but is that functional for SARS-CoV-2 entry?
por: Scagnolari, Carolina, et al.
Publicado: (2021)

SARS-CoV-2 Entry Genes Expression in Relation with Interferon Response in Cystic Fibrosis Patients
por: Bitossi, Camilla, et al.
Publicado: (2021)

NRF2 Antioxidant Response and Interferon-Stimulated Genes Are Differentially Expressed in Respiratory-Syncytial-Virus- and Rhinovirus-Infected Hospitalized Children
por: Sorrentino, Leonardo, et al.
Publicado: (2023)

A single centre study of viral community-acquired pneumonia in children: No evidence of SARS-CoV-2 from October 2019 to March 2020
por: Mancino, Enrica, et al.
Publicado: (2020)

Anti‐IFN‐α/‐ω neutralizing antibodies from COVID‐19 patients correlate with downregulation of IFN response and laboratory biomarkers of disease severity
por: Frasca, Federica, et al.
Publicado: (2022)

Differential induction of type I and III interferon genes in the upper respiratory tract of patients with coronavirus disease 2019 (COVID-19)
por: Scagnolari, Carolina, et al.
Publicado: (2021)

No detection of SARS-CoV-2 in cystic fibrosis patients at the Regional (Lazio) Reference Center for CF in Italy
por: Scagnolari, Carolina, et al.
Publicado: (2020)

Human bocavirus in children hospitalized for acute respiratory tract infection in Rome
por: Petrarca, Laura, et al.
Publicado: (2019)

Will children reveal their secret? The coronavirus dilemma
por: Cristiani, Luca, et al.
Publicado: (2020)

Distribution of Interferon Lambda 4 Single Nucleotide Polymorphism rs11322783 Genotypes in Patients with COVID-19
por: Sorrentino, Leonardo, et al.
Publicado: (2022)

KI and WU Polyomavirus in Respiratory Samples of SARS-CoV-2 Infected Patients
por: Prezioso, Carla, et al.
Publicado: (2021)

Common Microbial Genital Infections and Their Impact on the Innate Immune Response to HPV in Cervical Cells
por: Fracella, Matteo, et al.
Publicado: (2022)

Nasal Microbiota in RSV Bronchiolitis
por: Schippa, Serena, et al.
Publicado: (2020)

Analysis of type I IFN response and T cell activation in severe COVID-19/HIV-1 coinfection: A case report
por: d’Ettorre, Gabriella, et al.
Publicado: (2020)

High frequency of neutralizing antibodies to type I Interferon in HIV-1 patients hospitalized for COVID-19
por: Scordio, Mirko, et al.
Publicado: (2022)

Viral community acquired pneumonia at the emergency department: Report from the pre COVID‐19 age
por: Spagnolello, Ornella, et al.
Publicado: (2021)

Alteration of type I interferon response is associated with subclinical atherosclerosis in virologically suppressed HIV‐1‐infected male patients
por: Santinelli, Letizia, et al.
Publicado: (2021)

Probiotics and COVID-19
por: Ceccarelli, Giancarlo, et al.
Publicado: (2020)

Respiratory syncytial virus bronchiolitis, weather conditions and air pollution in an Italian urban area: An observational study
por: Nenna, Raffaella, et al.
Publicado: (2017)

Virological and clinical characterization of respiratory infections in children attending an emergency department during the first autumn–winter circulation of pandemic A (H1N1) 2009 influenza virus
por: Pierangeli, A., et al.
Publicado: (2011)

Type I interferons can be detected in respiratory swabs from SARS-Cov-2 infected patients
por: Antonelli, Guido, et al.
Publicado: (2020)

Differential expression of Type I interferon and inflammatory genes in SARS‐CoV‐2‐infected patients treated with monoclonal antibodies
por: Maddaloni, Luca, et al.
Publicado: (2023)

E-cigarettes and youth: an unresolved Public Health concern
por: Virgili, Fabrizio, et al.
Publicado: (2022)

Natural Flavonoid Derivatives Have Pan-Coronavirus Antiviral Activity
por: Mori, Mattia, et al.
Publicado: (2023)

The Key Role of Lung Ultrasound in the Diagnosis of a Mature Cystic Teratoma in a Child with Suspected Difficult to Treat Pneumonia: A Case Report
por: Iovine, Elio, et al.
Publicado: (2022)

Age Limit in Bronchiolitis Diagnosis: 6 or 12 Months?
por: Nenna, Raffaella, et al.
Publicado: (2020)

O485 Recently identified viruses contribute significantly to acute respiratory infections in children
por: Pierangeli, A., et al.
Publicado: (2007)

Gut Microbial Translocation in Critically Ill Children and Effects of Supplementation with Pre- and Pro Biotics
por: Papoff, Paola, et al.
Publicado: (2012)

Bordetella pertussis in infants hospitalized for acute respiratory symptoms remains a concern
por: Nicolai, Ambra, et al.
Publicado: (2013)

Is There a Chance of Normal Life in Severe Laryngeal web
por: Nenna, Raffaella, et al.
Publicado: (2021)

Modulation of Phenylalanine and Tyrosine Metabolism in HIV-1 Infected Patients with Neurocognitive Impairment: Results from a Clinical Trial
por: Innocenti, Giuseppe P., et al.
Publicado: (2020)

Analysis of Th17 and Tc17 Frequencies and Antiviral Defenses in Gut-Associated Lymphoid Tissue of Chronic HIV-1 Positive Patients
por: d'Ettorre, Gabriella, et al.
Publicado: (2015)

Human bocavirus infection in hospitalized children in Italy
por: Pierangeli, Alessandra, et al.
Publicado: (2008)

Preventing influenza and influenza like illness during Covid-19 pandemic: A call for action
por: d'Ettorre, Gabriele, et al.
Publicado: (2022)

Potential IFNγ Modulation of Inflammasome Pathway in Chlamydia trachomatis Infected Synovial Cells
por: Filardo, Simone, et al.
Publicado: (2021)

Clinical Effects of Oral Bacteriotherapy on Anal HPV Infection and Related Dysplasia in HIV-Positive MSM: Results from the “HPVinHIV” Trial
por: Cavallari, Eugenio Nelson, et al.
Publicado: (2021)

Clearance of human papillomavirus related anal condylomas after oral and endorectal multistrain probiotic supplementation in an HIV positive male: A case report
por: Ceccarelli, Giancarlo, et al.
Publicado: (2018)

An Italian Multicenter Study on the Epidemiology of Respiratory Syncytial Virus During SARS-CoV-2 Pandemic in Hospitalized Children
por: Nenna, Raffaella, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_l4rljttp3uisv5rrdhtgjiba8r