Cargando…

Analysis of Survival of Patients Hospitalized with COVID-19 in Espírito Santo, Brazil

Objective: To analyze the survival of patients hospitalized with COVID-19 and its associated factors. Methods: Retrospective study of survival analysis in individuals notified and hospitalized with COVID-19 in the state of Espírito Santo, Brazil. As data source, the reports of hospitalized patients...

Descripción completa

Detalles Bibliográficos
Autores principales: Garbin, Juliana Rodrigues Tovar, Leite, Franciéle Marabotti Costa, Lopes-Júnior, Luís Carlos, Dell’Antonio, Cristiano Soares da Silva, Dell’Antonio, Larissa Soares, dos Santos, Ana Paula Brioschi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9315540/
https://www.ncbi.nlm.nih.gov/pubmed/35886560
http://dx.doi.org/10.3390/ijerph19148709
_version_ 1784754587188592640
author Garbin, Juliana Rodrigues Tovar
Leite, Franciéle Marabotti Costa
Lopes-Júnior, Luís Carlos
Dell’Antonio, Cristiano Soares da Silva
Dell’Antonio, Larissa Soares
dos Santos, Ana Paula Brioschi
author_facet Garbin, Juliana Rodrigues Tovar
Leite, Franciéle Marabotti Costa
Lopes-Júnior, Luís Carlos
Dell’Antonio, Cristiano Soares da Silva
Dell’Antonio, Larissa Soares
dos Santos, Ana Paula Brioschi
author_sort Garbin, Juliana Rodrigues Tovar
collection PubMed
description Objective: To analyze the survival of patients hospitalized with COVID-19 and its associated factors. Methods: Retrospective study of survival analysis in individuals notified and hospitalized with COVID-19 in the state of Espírito Santo, Brazil. As data source, the reports of hospitalized patients in the period from 1 March 2020, to 31 July 2021 were used. The Cox regression analysis plus the proportional risk assessment (assumption) were used to compare hospitalization time until the occurrence of the event (death from COVID-19) associated with possible risk factors. Results: The sample comprised 9806 notifications of cases, with the occurrence of 1885 deaths from the disease (19.22%). The mean age of the group was 58 years (SD ± 18.3) and the mean hospital length of stay was 10.5 days (SD ± 11.8). The factors that presented a higher risk of death from COVID-19, associated with a lower survival rate, were non-work-related infection (HR = 4.33; p < 0.001), age group 60–79 years (HR: 1.62; p < 0.001) and 80 years or older (HR = 2.56; p < 0.001), presence of chronic cardiovascular disease (HR = 1.18; p = 0.028), chronic kidney disease (HR = 1.5; p = 0.004), smoking (HR = 1.41; p < 0.001), obesity (HR = 2.28; p < 0.001), neoplasms (HR = 1.81; p < 0.001) and chronic neurological disease (HR = 1.68; p < 0.001). Conclusion: It was concluded that non-work-related infection, age group above or equal to 60 years, presence of chronic cardiovascular disease, chronic kidney disease, chronic neurological disease, smoking, obesity and neoplasms were associated with a higher risk of death, and, therefore, a lower survival in Brazilian patients hospitalized with COVID-19. The identification of priority groups is crucial for Health Surveillance and can guide prevention, control, monitoring, and intervention strategies against the new coronavirus.
format Online
Article
Text
id pubmed-9315540
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-93155402022-07-27 Analysis of Survival of Patients Hospitalized with COVID-19 in Espírito Santo, Brazil Garbin, Juliana Rodrigues Tovar Leite, Franciéle Marabotti Costa Lopes-Júnior, Luís Carlos Dell’Antonio, Cristiano Soares da Silva Dell’Antonio, Larissa Soares dos Santos, Ana Paula Brioschi Int J Environ Res Public Health Article Objective: To analyze the survival of patients hospitalized with COVID-19 and its associated factors. Methods: Retrospective study of survival analysis in individuals notified and hospitalized with COVID-19 in the state of Espírito Santo, Brazil. As data source, the reports of hospitalized patients in the period from 1 March 2020, to 31 July 2021 were used. The Cox regression analysis plus the proportional risk assessment (assumption) were used to compare hospitalization time until the occurrence of the event (death from COVID-19) associated with possible risk factors. Results: The sample comprised 9806 notifications of cases, with the occurrence of 1885 deaths from the disease (19.22%). The mean age of the group was 58 years (SD ± 18.3) and the mean hospital length of stay was 10.5 days (SD ± 11.8). The factors that presented a higher risk of death from COVID-19, associated with a lower survival rate, were non-work-related infection (HR = 4.33; p < 0.001), age group 60–79 years (HR: 1.62; p < 0.001) and 80 years or older (HR = 2.56; p < 0.001), presence of chronic cardiovascular disease (HR = 1.18; p = 0.028), chronic kidney disease (HR = 1.5; p = 0.004), smoking (HR = 1.41; p < 0.001), obesity (HR = 2.28; p < 0.001), neoplasms (HR = 1.81; p < 0.001) and chronic neurological disease (HR = 1.68; p < 0.001). Conclusion: It was concluded that non-work-related infection, age group above or equal to 60 years, presence of chronic cardiovascular disease, chronic kidney disease, chronic neurological disease, smoking, obesity and neoplasms were associated with a higher risk of death, and, therefore, a lower survival in Brazilian patients hospitalized with COVID-19. The identification of priority groups is crucial for Health Surveillance and can guide prevention, control, monitoring, and intervention strategies against the new coronavirus. MDPI 2022-07-17 /pmc/articles/PMC9315540/ /pubmed/35886560 http://dx.doi.org/10.3390/ijerph19148709 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Garbin, Juliana Rodrigues Tovar
Leite, Franciéle Marabotti Costa
Lopes-Júnior, Luís Carlos
Dell’Antonio, Cristiano Soares da Silva
Dell’Antonio, Larissa Soares
dos Santos, Ana Paula Brioschi
Analysis of Survival of Patients Hospitalized with COVID-19 in Espírito Santo, Brazil
title Analysis of Survival of Patients Hospitalized with COVID-19 in Espírito Santo, Brazil
title_full Analysis of Survival of Patients Hospitalized with COVID-19 in Espírito Santo, Brazil
title_fullStr Analysis of Survival of Patients Hospitalized with COVID-19 in Espírito Santo, Brazil
title_full_unstemmed Analysis of Survival of Patients Hospitalized with COVID-19 in Espírito Santo, Brazil
title_short Analysis of Survival of Patients Hospitalized with COVID-19 in Espírito Santo, Brazil
title_sort analysis of survival of patients hospitalized with covid-19 in espírito santo, brazil
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9315540/
https://www.ncbi.nlm.nih.gov/pubmed/35886560
http://dx.doi.org/10.3390/ijerph19148709
work_keys_str_mv AT garbinjulianarodriguestovar analysisofsurvivalofpatientshospitalizedwithcovid19inespiritosantobrazil
AT leitefrancielemarabotticosta analysisofsurvivalofpatientshospitalizedwithcovid19inespiritosantobrazil
AT lopesjuniorluiscarlos analysisofsurvivalofpatientshospitalizedwithcovid19inespiritosantobrazil
AT dellantoniocristianosoaresdasilva analysisofsurvivalofpatientshospitalizedwithcovid19inespiritosantobrazil
AT dellantoniolarissasoares analysisofsurvivalofpatientshospitalizedwithcovid19inespiritosantobrazil
AT dossantosanapaulabrioschi analysisofsurvivalofpatientshospitalizedwithcovid19inespiritosantobrazil