Cargando…

The Biological Properties of the SARS-CoV-2 Cameroon Variant Spike: An Intermediate between the Alpha and Delta Variants

An analysis of the structural effect of the mutations of the B.1.640.2 (IHU) Spike Receptor Binding Domain (RBD) and N-terminal Domain (NTD) is reported along with a comparison with the sister lineage B.1.640.1. and a selection of variants of concern. The effect of the mutations on the RBD–ACE2 inte...

Descripción completa

Detalles Bibliográficos
Autores principales:	Pascarella, Stefano, Bianchi, Martina, Giovanetti, Marta, Benvenuto, Domenico, Borsetti, Alessandra, Cauda, Roberto, Cassone, Antonio, Ciccozzi, Massimo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9315702/ https://www.ncbi.nlm.nih.gov/pubmed/35890058 http://dx.doi.org/10.3390/pathogens11070814

Ejemplares similares

Shortening Epitopes to Survive: The Case of SARS-CoV-2 Lambda Variant
por: Pascarella, Stefano, et al.
Publicado: (2021)

The value of electrostatic potentials of the spike receptor binding and N-terminal domains in addressing transmissibility and infectivity of SARS-CoV-2 variants of concern
por: Pascarella, Stefano, et al.
Publicado: (2022)

Peculiar Variations of the Electrostatic Potential of Spike Protein N-terminal Domain Associated with the Emergence of Successive SARS-CoV-2 Omicron Lineages
por: Pascarella, Stefano, et al.
Publicado: (2023)

Evolutionary analysis of SARS-CoV-2: how mutation of Non-Structural Protein 6 (NSP6) could affect viral autophagy
por: Benvenuto, Domenico, et al.
Publicado: (2020)

SARS‐CoV‐2 B.1.617 Indian variants: Are electrostatic potential changes responsible for a higher transmission rate?
por: Pascarella, Stefano, et al.
Publicado: (2021)

Genetic and Structural Data on the SARS-CoV-2 Omicron BQ.1 Variant Reveal Its Low Potential for Epidemiological Expansion
por: Scarpa, Fabio, et al.
Publicado: (2022)

Sars-CoV-2 Envelope and Membrane Proteins: Structural Differences Linked to Virus Characteristics?
por: Bianchi, Martina, et al.
Publicado: (2020)

SARS-Cov-2 ORF3a: Mutability and function
por: Bianchi, Martina, et al.
Publicado: (2021)

SARS-CoV CH.1.1 Variant: Genomic and Structural Insight
por: Bazzani, Liliana, et al.
Publicado: (2023)

Integrative Genome-Based Survey of the SARS-CoV-2 Omicron XBB.1.16 Variant
por: Scarpa, Fabio, et al.
Publicado: (2023)

Genetic and structural genome-based survey reveals the low potential for epidemiological expansion of the SARS-CoV-2 XBB.1.5 sublineage
por: Scarpa, Fabio, et al.
Publicado: (2023)

Khosta: A Genetic and Structural Point of View of the Forgotten Virus
por: Scarpa, Fabio, et al.
Publicado: (2023)

Molecular In-Depth on the Epidemiological Expansion of SARS-CoV-2 XBB.1.5
por: Scarpa, Fabio, et al.
Publicado: (2023)

Molecular Epidemiology of HIV-1 in African Countries: A Comprehensive Overview
por: Giovanetti, Marta, et al.
Publicado: (2020)

Update on the Phylodynamic and Genetic Variability of Marburg Virus
por: Scarpa, Fabio, et al.
Publicado: (2023)

Two sides of the same coin: the N-terminal and the receptor binding domains of SARS-CoV-2 Spike
por: Ciccozzi, Massimo, et al.
Publicado: (2023)

Human Immunodeficiency Virus Type 2: The Neglected Threat
por: Ceccarelli, Giancarlo, et al.
Publicado: (2021)

Application of the ARIMA model on the COVID-2019 epidemic dataset
por: Benvenuto, Domenico, et al.
Publicado: (2020)

Multicomponent vaccines to fight SARS-CoV-2 variants of concern
por: Cassone, Antonio, et al.
Publicado: (2021)

Assessment of mutations on RBD in the Spike protein of SARS-CoV-2 Alpha, Delta and Omicron variants
por: da Costa, Clauber Henrique Souza, et al.
Publicado: (2022)

The variants question: What is the problem?
por: Zella, Davide, et al.
Publicado: (2021)

Evolution patterns of SARS-CoV-2: Snapshot on its genome variants
por: Giovanetti, Marta, et al.
Publicado: (2021)

SARS‐CoV‐2 Alpha, Beta, and Delta variants display enhanced Spike‐mediated syncytia formation
por: Rajah, Maaran Michael, et al.
Publicado: (2021)

Monitoring Monkeypox: Safeguarding Global Health through Rapid Response and Global Surveillance
por: Giovanetti, Marta, et al.
Publicado: (2023)

Delta spike P681R mutation enhances SARS-CoV-2 fitness over Alpha variant
por: Liu, Yang, et al.
Publicado: (2021)

Delta spike P681R mutation enhances SARS-CoV-2 fitness over Alpha variant
por: Liu, Yang, et al.
Publicado: (2022)

Effect of Covid-19 Vaccination on Transmission of Alpha and Delta Variants
por: Eyre, David W., et al.
Publicado: (2022)

Analysis of the N-glycosylation profiles of the spike proteins from the Alpha, Beta, Gamma, and Delta variants of SARS-CoV-2
por: Wang, Dongxia, et al.
Publicado: (2023)

HIV-1–Host Interaction in Gut-Associated Lymphoid Tissue (GALT): Effects on Local Environment and Comorbidities
por: Moretti, Sonia, et al.
Publicado: (2023)

Delta and the Variants
por: Suresh, Mithun R., et al.
Publicado: (2022)

SARS-CoV-2 Recombinants: Genomic Comparison between XBF and Its Parental Lineages
por: Scarpa, Fabio, et al.
Publicado: (2023)

Severity of COVID-19 cases in the months of predominance of the Alpha and Delta variants
por: Florensa, D., et al.
Publicado: (2022)

Gut Microbiota and COVID-19: Potential Implications for Disease Severity
por: Rocchi, Giulia, et al.
Publicado: (2022)

Joining Forces against Antibiotic Resistance: The One Health Solution
por: Cella, Eleonora, et al.
Publicado: (2023)

The impact of spike mutated variants of SARS-CoV2 [Alpha, Beta, Gamma, Delta, and Lambda] on the efficacy of subunit recombinant vaccines
por: Mohammadi, Mehrdad, et al.
Publicado: (2021)

SARS CoV-2 reinfection rate is higher in the Omicron variant than in the Alpha and Delta variants
por: Özüdoğru, Osman, et al.
Publicado: (2022)

Replacement of the Alpha variant of SARS-CoV-2 by the Delta variant in Lebanon between April and June 2021
por: Merhi, Georgi, et al.
Publicado: (2022)

The frequency of defective genomes in Omicron differs from that of the Alpha, Beta and Delta variants
por: Campos, Carolina, et al.
Publicado: (2022)

COVID-19 long-term sequelae: Omicron versus Alpha and Delta variants
por: Hernández-Aceituno, Ana, et al.
Publicado: (2023)

SARS-CoV-2 shifting transmission dynamics and hidden reservoirs potentially limit efficacy of public health interventions in Italy
por: Giovanetti, Marta, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_r3ejgs2ivaoa6tnda0fmrp7pvd