Extracellular Citrate Treatment Induces HIF1α Degradation and Inhibits the Growth of Low-Glycolytic Hepatocellular Carcinoma under Hypoxia

SIMPLE SUMMARY: Patients with low-glycolytic hepatocellular carcinoma (HCC) show better clinical outcomes than those with hypoxic and high-glycolytic HCC. Low-glycolytic HCCs seem to utilize carbon sources other than glucose for metabolic fuel and tumor growth. However, by increasing tumor size, its...

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Detalles Bibliográficos
Autores principales: Kim, Seon Yoo, Kim, Dongwoo, Kim, Jisu, Ko, Hae Young, Kim, Won Jin, Park, Youngjoo, Lee, Hye Won, Han, Dai Hoon, Kim, Kyung Sik, Park, Sunghyouk, Lee, Misu, Yun, Mijin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9315704/
https://www.ncbi.nlm.nih.gov/pubmed/35884416
http://dx.doi.org/10.3390/cancers14143355

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9315704/
https://www.ncbi.nlm.nih.gov/pubmed/35884416
http://dx.doi.org/10.3390/cancers14143355

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