Phosphodiesterase-4 Inhibitor Roflumilast-Mediated Protective Effect in Sepsis-Induced Late-Phase Event of Acute Kidney Injury: A Narrative Review

Severe infections such as viral, bacterial, or fungal sepsis can cause an inflammatory response in the host, leading to organ failure and septic shock—phosphodiesterase-4 (PDE-4) inhibiting related agents from suppressing cyclic adenosine monophosphate (cAMP) degradation. Regulatory organisations ha...

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Detalles Bibliográficos
Autores principales: Kazmi, Imran, Al-Abbasi, Fahad A., Afzal, Muhammad, Nadeem, Muhammad Shahid, Altayb, Hisham N., Gupta, Gaurav
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9315747/
https://www.ncbi.nlm.nih.gov/pubmed/35890197
http://dx.doi.org/10.3390/ph15070899

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9315747/
https://www.ncbi.nlm.nih.gov/pubmed/35890197
http://dx.doi.org/10.3390/ph15070899

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