AIMing 2 treat atherosclerosis

The AIM2 inflammasome is activated by host and pathogen DNA. Work from the past 5 years indicates that the AIM2 inflammasome has an important role in advanced atherosclerosis driven by clonal haematopoiesis and possibly in atherosclerosis accelerated by acute infection. Therefore, the AIM2 inflammas...

Descripción completa

Detalles Bibliográficos
Autores principales: Soehnlein, Oliver, Tall, Alan R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Comment
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9315844/
https://www.ncbi.nlm.nih.gov/pubmed/35882998
http://dx.doi.org/10.1038/s41569-022-00755-0
_version_ 1784754662089424896
author Soehnlein, Oliver
Tall, Alan R.
author_facet Soehnlein, Oliver
Tall, Alan R.
author_sort Soehnlein, Oliver
collection PubMed
description The AIM2 inflammasome is activated by host and pathogen DNA. Work from the past 5 years indicates that the AIM2 inflammasome has an important role in advanced atherosclerosis driven by clonal haematopoiesis and possibly in atherosclerosis accelerated by acute infection. Therefore, the AIM2 inflammasome might be an important target for precision medicine.
format Online
Article
Text
id pubmed-9315844
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher Nature Publishing Group UK
record_format MEDLINE/PubMed
spelling pubmed-93158442022-07-26 AIMing 2 treat atherosclerosis Soehnlein, Oliver Tall, Alan R. Nat Rev Cardiol Comment The AIM2 inflammasome is activated by host and pathogen DNA. Work from the past 5 years indicates that the AIM2 inflammasome has an important role in advanced atherosclerosis driven by clonal haematopoiesis and possibly in atherosclerosis accelerated by acute infection. Therefore, the AIM2 inflammasome might be an important target for precision medicine. Nature Publishing Group UK 2022-07-26 2022 /pmc/articles/PMC9315844/ /pubmed/35882998 http://dx.doi.org/10.1038/s41569-022-00755-0 Text en © Springer Nature Limited 2022 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Comment
Soehnlein, Oliver
Tall, Alan R.
AIMing 2 treat atherosclerosis
title AIMing 2 treat atherosclerosis
title_full AIMing 2 treat atherosclerosis
title_fullStr AIMing 2 treat atherosclerosis
title_full_unstemmed AIMing 2 treat atherosclerosis
title_short AIMing 2 treat atherosclerosis
title_sort aiming 2 treat atherosclerosis
topic Comment
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9315844/
https://www.ncbi.nlm.nih.gov/pubmed/35882998
http://dx.doi.org/10.1038/s41569-022-00755-0
work_keys_str_mv AT soehnleinoliver aiming2treatatherosclerosis
AT tallalanr aiming2treatatherosclerosis

Ejemplares similares