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Tumor cell SYK expression modulates the tumor immune microenvironment composition in human cancer via TNF-α dependent signaling

BACKGROUND: The expression of SYK in cancer cells has been associated with both tumor promoting and tumor suppressive effects. Despite being proposed as anticancer therapeutic target, the possible role of SYK in modulating local adaptive antitumor immune responses remains uncertain. Using detailed a...

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Detalles Bibliográficos
Autores principales:	Aguirre-Ducler, Adam, Gianino, Nicole, Villarroel-Espindola, Franz, Desai, Shruti, Tang, Daiwei, Zhao, Hongyu, Syrigos, Konstantinos, Trepicchio, William L, Kannan, Karuppiah, Gregory, Richard C, Schalper, Kurt A
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2022
Materias:	Clinical/Translational Cancer Immunotherapy
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9315908/ https://www.ncbi.nlm.nih.gov/pubmed/35868661 http://dx.doi.org/10.1136/jitc-2022-005113

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