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Magnesium Status and Ca/Mg Ratios in a Series of Children and Adolescents with Chronic Diseases

Magnesium (Mg) is an essential divalent cation involved in various enzymatic reactions that regulate vital biological functions. The main goal was to evaluate Mg status and its association with nutritional indicators in 78 children and adolescents with chronic diseases. We assessed anthropometric, b...

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Autores principales: Escobedo-Monge, Marlene Fabiola, Barrado, Enrique, Parodi-Román, Joaquín, Escobedo-Monge, María Antonieta, Torres-Hinojal, María Carmen, Marugán-Miguelsanz, José Manuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9315923/
https://www.ncbi.nlm.nih.gov/pubmed/35889897
http://dx.doi.org/10.3390/nu14142941
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author Escobedo-Monge, Marlene Fabiola
Barrado, Enrique
Parodi-Román, Joaquín
Escobedo-Monge, María Antonieta
Torres-Hinojal, María Carmen
Marugán-Miguelsanz, José Manuel
author_facet Escobedo-Monge, Marlene Fabiola
Barrado, Enrique
Parodi-Román, Joaquín
Escobedo-Monge, María Antonieta
Torres-Hinojal, María Carmen
Marugán-Miguelsanz, José Manuel
author_sort Escobedo-Monge, Marlene Fabiola
collection PubMed
description Magnesium (Mg) is an essential divalent cation involved in various enzymatic reactions that regulate vital biological functions. The main goal was to evaluate Mg status and its association with nutritional indicators in 78 children and adolescents with chronic diseases. We assessed anthropometric, biochemical, diet, body composition, and bone densitometry valuations. Serum Mg and Ca levels were determined using the standardized method and diet calcium (Ca) and Mg consumption by a prospective 72 h diet survey. Mean serum Ca (9.9 mg/dL), Mg (2.08 mg/dL) dietary Ca (102% DRI: Dietary Reference Intake), and Mg intake (105% DRI) were normal. A total of 45% had hypomagnesemia, 12% had hypermagnesemia, and 26% and 24% had inadequate and high Mg intake, respectively. Only 6% of patients had poor Mg intake and hypomagnesemia, and 54% and 90% of our series had an elevated serum Ca/Mg ratio > 4.70 (mean 4.79) and a low Ca/Mg intake ratio < 1.70 (mean 1.06), respectively. Both Ca/Mg ratios were linked with the risk of developing other chronic conditions such as cardiovascular disease, type 2 diabetes, syndrome metabolic, and even several cancers. Therefore, 79% of children and adolescents with chronic diseases were at elevated risk of having abnormal Mg status and developing other chronic illnesses.
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spelling pubmed-93159232022-07-27 Magnesium Status and Ca/Mg Ratios in a Series of Children and Adolescents with Chronic Diseases Escobedo-Monge, Marlene Fabiola Barrado, Enrique Parodi-Román, Joaquín Escobedo-Monge, María Antonieta Torres-Hinojal, María Carmen Marugán-Miguelsanz, José Manuel Nutrients Article Magnesium (Mg) is an essential divalent cation involved in various enzymatic reactions that regulate vital biological functions. The main goal was to evaluate Mg status and its association with nutritional indicators in 78 children and adolescents with chronic diseases. We assessed anthropometric, biochemical, diet, body composition, and bone densitometry valuations. Serum Mg and Ca levels were determined using the standardized method and diet calcium (Ca) and Mg consumption by a prospective 72 h diet survey. Mean serum Ca (9.9 mg/dL), Mg (2.08 mg/dL) dietary Ca (102% DRI: Dietary Reference Intake), and Mg intake (105% DRI) were normal. A total of 45% had hypomagnesemia, 12% had hypermagnesemia, and 26% and 24% had inadequate and high Mg intake, respectively. Only 6% of patients had poor Mg intake and hypomagnesemia, and 54% and 90% of our series had an elevated serum Ca/Mg ratio > 4.70 (mean 4.79) and a low Ca/Mg intake ratio < 1.70 (mean 1.06), respectively. Both Ca/Mg ratios were linked with the risk of developing other chronic conditions such as cardiovascular disease, type 2 diabetes, syndrome metabolic, and even several cancers. Therefore, 79% of children and adolescents with chronic diseases were at elevated risk of having abnormal Mg status and developing other chronic illnesses. MDPI 2022-07-18 /pmc/articles/PMC9315923/ /pubmed/35889897 http://dx.doi.org/10.3390/nu14142941 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Escobedo-Monge, Marlene Fabiola
Barrado, Enrique
Parodi-Román, Joaquín
Escobedo-Monge, María Antonieta
Torres-Hinojal, María Carmen
Marugán-Miguelsanz, José Manuel
Magnesium Status and Ca/Mg Ratios in a Series of Children and Adolescents with Chronic Diseases
title Magnesium Status and Ca/Mg Ratios in a Series of Children and Adolescents with Chronic Diseases
title_full Magnesium Status and Ca/Mg Ratios in a Series of Children and Adolescents with Chronic Diseases
title_fullStr Magnesium Status and Ca/Mg Ratios in a Series of Children and Adolescents with Chronic Diseases
title_full_unstemmed Magnesium Status and Ca/Mg Ratios in a Series of Children and Adolescents with Chronic Diseases
title_short Magnesium Status and Ca/Mg Ratios in a Series of Children and Adolescents with Chronic Diseases
title_sort magnesium status and ca/mg ratios in a series of children and adolescents with chronic diseases
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9315923/
https://www.ncbi.nlm.nih.gov/pubmed/35889897
http://dx.doi.org/10.3390/nu14142941
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