Sphingomyelin Depletion Inhibits CXCR4 Dynamics and CXCL12-Mediated Directed Cell Migration in Human T Cells

Sphingolipids, ceramides and cholesterol are integral components of cellular membranes, and they also play important roles in signal transduction by regulating the dynamics of membrane receptors through their effects on membrane fluidity. Here, we combined biochemical and functional assays with sing...

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Detalles Bibliográficos
Autores principales: Gardeta, Sofía R., García-Cuesta, Eva M., D’Agostino, Gianluca, Soler Palacios, Blanca, Quijada-Freire, Adriana, Lucas, Pilar, Bernardino de la Serna, Jorge, Gonzalez-Riano, Carolina, Barbas, Coral, Rodríguez-Frade, José Miguel, Mellado, Mario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9315926/
https://www.ncbi.nlm.nih.gov/pubmed/35903108
http://dx.doi.org/10.3389/fimmu.2022.925559

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