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JAK2 Alterations in Acute Lymphoblastic Leukemia: Molecular Insights for Superior Precision Medicine Strategies

Acute lymphoblastic leukemia (ALL) is the most common pediatric cancer, arising from immature lymphocytes that show uncontrolled proliferation and arrested differentiation. Genomic alterations affecting Janus kinase 2 (JAK2) correlate with some of the poorest outcomes within the Philadelphia-like su...

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Detalles Bibliográficos
Autores principales:	Downes, Charlotte EJ., McClure, Barbara J., McDougal, Daniel P., Heatley, Susan L., Bruning, John B., Thomas, Daniel, Yeung, David T., White, Deborah L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Cell and Developmental Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9315936/ https://www.ncbi.nlm.nih.gov/pubmed/35903543 http://dx.doi.org/10.3389/fcell.2022.942053

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