PEDF Deletion Induces Senescence and Defects in Phagocytosis in the RPE

The retinal pigment epithelium (RPE) expresses the Serpinf1 gene to produce pigment epithelium-derived factor (PEDF), a retinoprotective protein that is downregulated with cell senescence, aging and retinal degenerations. We determined the expression of senescence-associated genes in the RPE of 3-mo...

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Detalles Bibliográficos
Autores principales: Rebustini, Ivan T., Crawford, Susan E., Becerra, S. Patricia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9316002/
https://www.ncbi.nlm.nih.gov/pubmed/35887093
http://dx.doi.org/10.3390/ijms23147745

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9316002/
https://www.ncbi.nlm.nih.gov/pubmed/35887093
http://dx.doi.org/10.3390/ijms23147745

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