Succinimido–Ferrocidiphenol Complexed with Cyclodextrins Inhibits Glioblastoma Tumor Growth In Vitro and In Vivo without Noticeable Adverse Toxicity

SuccFerr (N-[4-ferrocenyl,5-5-bis (4-hydroxyphenyl)-pent-4-enyl]-succinimide) has remarkable antiproliferative effects in vitro, attributed to the formation of a stabilized quinone methide. The present article reports in vivo results for a possible preclinical study. SuccFerr is lipophilic and insol...

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Detalles Bibliográficos
Autores principales: Najlaoui, Feten, Busser, Benoit, Taïwe, Germain Sotoing, Pigeon, Pascal, Sturm, Nathalie, Giovannini, Diane, Marrakchi, Naziha, Rhouma, Ali, Jaouen, Gérard, Gibaud, Stéphane, De Waard, Michel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9316017/
https://www.ncbi.nlm.nih.gov/pubmed/35889527
http://dx.doi.org/10.3390/molecules27144651

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