Tuning Design Parameters of ICAM-1-Targeted 3DNA Nanocarriers to Optimize Pulmonary Targeting Depending on Drug Type

3DNA holds promise as a carrier for drugs that can be intercalated into its core or linked to surface arms. Coupling 3DNA to an antibody targeting intercellular adhesion molecule 1 (ICAM-1) results in high lung-specific biodistributions in vivo. While the role of individual parameters on ICAM-1 targ...

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Detalles Bibliográficos
Autores principales: Roki, Nikša, Solomon, Melani, Bowers, Jessica, Getts, Lori, Getts, Robert C., Muro, Silvia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9316040/
https://www.ncbi.nlm.nih.gov/pubmed/35890393
http://dx.doi.org/10.3390/pharmaceutics14071496

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9316040/
https://www.ncbi.nlm.nih.gov/pubmed/35890393
http://dx.doi.org/10.3390/pharmaceutics14071496

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