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C8orf76 Modulates Ferroptosis in Liver Cancer via Transcriptionally Up-Regulating SLC7A11

SIMPLE SUMMARY: Chromosome 8 open reading frame 76 (C8orf76), a novel gene located in the nucleus, is highly expressed in many tumor types. Here, we present novel insights into the molecular mechanism and function of C8orf76 in HCC via in vitro and in vivo assays. On the one hand, C8orf76 could play...

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Detalles Bibliográficos
Autores principales: Li, Duguang, Pan, Junhai, Zhang, Yiyin, Li, Yirun, Jin, Shengxi, Zhong, Cheng, Chen, Peng, Ma, Jingjing, Hu, Wendi, Fan, Xiaoxiao, Lin, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9316296/
https://www.ncbi.nlm.nih.gov/pubmed/35884471
http://dx.doi.org/10.3390/cancers14143410