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Scalable, Robust and Highly Productive Novel Convecdiff Membrane Platform for mAb Capture

The recombinant monoclonal antibody capture step represents the current bottleneck in downstream processing. Protein A resins are diffusion-limited chromatography materials which require low flow rates to achieve a binding capacity above 30 g L(−1) with the result of low productivity. Here, we prese...

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Detalles Bibliográficos
Autores principales: Grünberg, Mario, Kuchemüller, Kim B., Töppner, Katrin, Busse, Ricarda A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9316305/
https://www.ncbi.nlm.nih.gov/pubmed/35877882
http://dx.doi.org/10.3390/membranes12070677