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Scalable, Robust and Highly Productive Novel Convecdiff Membrane Platform for mAb Capture
The recombinant monoclonal antibody capture step represents the current bottleneck in downstream processing. Protein A resins are diffusion-limited chromatography materials which require low flow rates to achieve a binding capacity above 30 g L(−1) with the result of low productivity. Here, we prese...
Autores principales: | Grünberg, Mario, Kuchemüller, Kim B., Töppner, Katrin, Busse, Ricarda A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9316305/ https://www.ncbi.nlm.nih.gov/pubmed/35877882 http://dx.doi.org/10.3390/membranes12070677 |
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