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Choroidal Thickness Increase after Subliminal Transscleral Cyclophotocoagulation

Background: The purpose of this study is to estimate the success rate of subliminal transscleral cyclophotocoagulation for refractory glaucoma and to determine the correlation between the decrease in intraocular pressure and the variation in choroidal thickness. Methods: A pre–post study was conduct...

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Autores principales: Baltă, Florian, Dinu, Valentin, Zemba, Mihail, Baltă, George, Barac, Andreea Diana, Schmitzer, Speranța, Dragosloveanu, Christiana Diana Maria, Barac, Ramona Ileana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9316627/
https://www.ncbi.nlm.nih.gov/pubmed/35885419
http://dx.doi.org/10.3390/diagnostics12071513
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author Baltă, Florian
Dinu, Valentin
Zemba, Mihail
Baltă, George
Barac, Andreea Diana
Schmitzer, Speranța
Dragosloveanu, Christiana Diana Maria
Barac, Ramona Ileana
author_facet Baltă, Florian
Dinu, Valentin
Zemba, Mihail
Baltă, George
Barac, Andreea Diana
Schmitzer, Speranța
Dragosloveanu, Christiana Diana Maria
Barac, Ramona Ileana
author_sort Baltă, Florian
collection PubMed
description Background: The purpose of this study is to estimate the success rate of subliminal transscleral cyclophotocoagulation for refractory glaucoma and to determine the correlation between the decrease in intraocular pressure and the variation in choroidal thickness. Methods: A pre–post study was conducted over a period of 3 years, including 81 eyes from 67 patients with different types of drug-refractory glaucoma who underwent subliminal transscleral cyclophotocoagulation. The variables included best-corrected visual acuity, intraocular pressure and choroidal thickness. Results: We observed the following success rates (defined as IOP < 21 mmHg): 80% at 1 month (65 patients), 74% at 3 months (60 patients), 64% at 6 months (52 patients) and 50.6% at 1 year (41 patients). A strong correlation was noted between the decrease in intraocular pressure and the increase in the average choroidal thickness at 1 year (318.42 µm) compared to the average preoperative thickness (291.78 µm). A correlation of increased choroidal thickness at 1-month with the success rate of the procedure was also observed. Conclusions: We observed a statistically significant correlation between the success rate, decrease in intraocular pressure and choroidal thickness. The correlation of increased choroidal thickness at 1-month with the success rate of the procedure could be used clinically as a predictive factor for the final outcome of patients. Further experimental research is warranted to determine whether the increase in choroidal thickness after subliminal transscleral cyclophotocoagulation is indeed evidence of increased uveoscleral drainage.
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spelling pubmed-93166272022-07-27 Choroidal Thickness Increase after Subliminal Transscleral Cyclophotocoagulation Baltă, Florian Dinu, Valentin Zemba, Mihail Baltă, George Barac, Andreea Diana Schmitzer, Speranța Dragosloveanu, Christiana Diana Maria Barac, Ramona Ileana Diagnostics (Basel) Article Background: The purpose of this study is to estimate the success rate of subliminal transscleral cyclophotocoagulation for refractory glaucoma and to determine the correlation between the decrease in intraocular pressure and the variation in choroidal thickness. Methods: A pre–post study was conducted over a period of 3 years, including 81 eyes from 67 patients with different types of drug-refractory glaucoma who underwent subliminal transscleral cyclophotocoagulation. The variables included best-corrected visual acuity, intraocular pressure and choroidal thickness. Results: We observed the following success rates (defined as IOP < 21 mmHg): 80% at 1 month (65 patients), 74% at 3 months (60 patients), 64% at 6 months (52 patients) and 50.6% at 1 year (41 patients). A strong correlation was noted between the decrease in intraocular pressure and the increase in the average choroidal thickness at 1 year (318.42 µm) compared to the average preoperative thickness (291.78 µm). A correlation of increased choroidal thickness at 1-month with the success rate of the procedure was also observed. Conclusions: We observed a statistically significant correlation between the success rate, decrease in intraocular pressure and choroidal thickness. The correlation of increased choroidal thickness at 1-month with the success rate of the procedure could be used clinically as a predictive factor for the final outcome of patients. Further experimental research is warranted to determine whether the increase in choroidal thickness after subliminal transscleral cyclophotocoagulation is indeed evidence of increased uveoscleral drainage. MDPI 2022-06-21 /pmc/articles/PMC9316627/ /pubmed/35885419 http://dx.doi.org/10.3390/diagnostics12071513 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Baltă, Florian
Dinu, Valentin
Zemba, Mihail
Baltă, George
Barac, Andreea Diana
Schmitzer, Speranța
Dragosloveanu, Christiana Diana Maria
Barac, Ramona Ileana
Choroidal Thickness Increase after Subliminal Transscleral Cyclophotocoagulation
title Choroidal Thickness Increase after Subliminal Transscleral Cyclophotocoagulation
title_full Choroidal Thickness Increase after Subliminal Transscleral Cyclophotocoagulation
title_fullStr Choroidal Thickness Increase after Subliminal Transscleral Cyclophotocoagulation
title_full_unstemmed Choroidal Thickness Increase after Subliminal Transscleral Cyclophotocoagulation
title_short Choroidal Thickness Increase after Subliminal Transscleral Cyclophotocoagulation
title_sort choroidal thickness increase after subliminal transscleral cyclophotocoagulation
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9316627/
https://www.ncbi.nlm.nih.gov/pubmed/35885419
http://dx.doi.org/10.3390/diagnostics12071513
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