Cargando…
An investigation of the constancy of effect in Cochrane systematic reviews in context with the assumptions for noninferiority trials
When designing a noninferiority (NI) study one of the most important steps is to set the noninferiority (NI) limit. The NI limit is an acceptable loss of efficacy for a new investigative treatment compared to an active control treatment – often standard care. The limit should be a value so small tha...
Autores principales: | , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9316704/ https://www.ncbi.nlm.nih.gov/pubmed/35879673 http://dx.doi.org/10.1186/s12874-022-01684-9 |