Single-cell multimodal analysis identifies common regulatory programs in synovial fibroblasts of rheumatoid arthritis patients and modeled TNF-driven arthritis

BACKGROUND: Synovial fibroblasts (SFs) are specialized cells of the synovium that provide nutrients and lubricants for the proper function of diarthrodial joints. Recent evidence appreciates the contribution of SF heterogeneity in arthritic pathologies. However, the normal SF profiles and the molecu...

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Detalles Bibliográficos
Autores principales: Armaka, Marietta, Konstantopoulos, Dimitris, Tzaferis, Christos, Lavigne, Matthieu D., Sakkou, Maria, Liakos, Anastasios, Sfikakis, Petros P., Dimopoulos, Meletios A., Fousteri, Maria, Kollias, George
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9316748/
https://www.ncbi.nlm.nih.gov/pubmed/35879783
http://dx.doi.org/10.1186/s13073-022-01081-3

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