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Brain Delivery of IGF1R5, a Single-Domain Antibody Targeting Insulin-like Growth Factor-1 Receptor

The ability of drugs and therapeutic antibodies to reach central nervous system (CNS) targets is greatly diminished by the blood–brain barrier (BBB). Receptor-mediated transcytosis (RMT), which is responsible for the transport of natural protein ligands across the BBB, was identified as a way to inc...

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Detalles Bibliográficos
Autores principales:	Yogi, Alvaro, Hussack, Greg, van Faassen, Henk, Haqqani, Arsalan S., Delaney, Christie E., Brunette, Eric, Sandhu, Jagdeep K., Hewitt, Melissa, Sulea, Traian, Kemmerich, Kristin, Stanimirovic, Danica B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9316817/ https://www.ncbi.nlm.nih.gov/pubmed/35890347 http://dx.doi.org/10.3390/pharmaceutics14071452

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