Cargando…
A Systematic Review of Treatment Outcome Predictors in Deep Brain Stimulation for Refractory Obsessive-Compulsive Disorder
Obsessive-compulsive disorder (OCD) is a chronic and debilitating mental disorder. Deep brain stimulation (DBS) is a promising approach for refractory OCD patients. Research aiming at treatment outcome prediction is vital to provide optimized treatments for different patients. The primary purpose of...
Autores principales: | , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9316868/ https://www.ncbi.nlm.nih.gov/pubmed/35884742 http://dx.doi.org/10.3390/brainsci12070936 |
_version_ | 1784754919261077504 |
---|---|
author | Ruan, Hanyang Wang, Yang Li, Zheqin Tong, Geya Wang, Zhen |
author_facet | Ruan, Hanyang Wang, Yang Li, Zheqin Tong, Geya Wang, Zhen |
author_sort | Ruan, Hanyang |
collection | PubMed |
description | Obsessive-compulsive disorder (OCD) is a chronic and debilitating mental disorder. Deep brain stimulation (DBS) is a promising approach for refractory OCD patients. Research aiming at treatment outcome prediction is vital to provide optimized treatments for different patients. The primary purpose of this systematic review was to collect and synthesize studies on outcome prediction of OCD patients with DBS implantations in recent years. This systematic review (PROSPERO registration number: CRD42022335585) followed the PRISMA (Preferred Reporting Items for Systematic Review and Meta-analysis) guidelines. The search was conducted using three different databases with the following search terms related to OCD and DBS. We identified a total of 3814 articles, and 17 studies were included in our review. A specific tract confirmed by magnetic resonance imaging (MRI) was predictable for DBS outcome regardless of implant targets, but inconsistencies still exist. Current studies showed various ways of successful treatment prediction. However, considering the heterogeneous results, we hope that future studies will use larger cohorts and more precise approaches for predictors and establish more personalized ways of DBS surgeries. |
format | Online Article Text |
id | pubmed-9316868 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-93168682022-07-27 A Systematic Review of Treatment Outcome Predictors in Deep Brain Stimulation for Refractory Obsessive-Compulsive Disorder Ruan, Hanyang Wang, Yang Li, Zheqin Tong, Geya Wang, Zhen Brain Sci Systematic Review Obsessive-compulsive disorder (OCD) is a chronic and debilitating mental disorder. Deep brain stimulation (DBS) is a promising approach for refractory OCD patients. Research aiming at treatment outcome prediction is vital to provide optimized treatments for different patients. The primary purpose of this systematic review was to collect and synthesize studies on outcome prediction of OCD patients with DBS implantations in recent years. This systematic review (PROSPERO registration number: CRD42022335585) followed the PRISMA (Preferred Reporting Items for Systematic Review and Meta-analysis) guidelines. The search was conducted using three different databases with the following search terms related to OCD and DBS. We identified a total of 3814 articles, and 17 studies were included in our review. A specific tract confirmed by magnetic resonance imaging (MRI) was predictable for DBS outcome regardless of implant targets, but inconsistencies still exist. Current studies showed various ways of successful treatment prediction. However, considering the heterogeneous results, we hope that future studies will use larger cohorts and more precise approaches for predictors and establish more personalized ways of DBS surgeries. MDPI 2022-07-17 /pmc/articles/PMC9316868/ /pubmed/35884742 http://dx.doi.org/10.3390/brainsci12070936 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Systematic Review Ruan, Hanyang Wang, Yang Li, Zheqin Tong, Geya Wang, Zhen A Systematic Review of Treatment Outcome Predictors in Deep Brain Stimulation for Refractory Obsessive-Compulsive Disorder |
title | A Systematic Review of Treatment Outcome Predictors in Deep Brain Stimulation for Refractory Obsessive-Compulsive Disorder |
title_full | A Systematic Review of Treatment Outcome Predictors in Deep Brain Stimulation for Refractory Obsessive-Compulsive Disorder |
title_fullStr | A Systematic Review of Treatment Outcome Predictors in Deep Brain Stimulation for Refractory Obsessive-Compulsive Disorder |
title_full_unstemmed | A Systematic Review of Treatment Outcome Predictors in Deep Brain Stimulation for Refractory Obsessive-Compulsive Disorder |
title_short | A Systematic Review of Treatment Outcome Predictors in Deep Brain Stimulation for Refractory Obsessive-Compulsive Disorder |
title_sort | systematic review of treatment outcome predictors in deep brain stimulation for refractory obsessive-compulsive disorder |
topic | Systematic Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9316868/ https://www.ncbi.nlm.nih.gov/pubmed/35884742 http://dx.doi.org/10.3390/brainsci12070936 |
work_keys_str_mv | AT ruanhanyang asystematicreviewoftreatmentoutcomepredictorsindeepbrainstimulationforrefractoryobsessivecompulsivedisorder AT wangyang asystematicreviewoftreatmentoutcomepredictorsindeepbrainstimulationforrefractoryobsessivecompulsivedisorder AT lizheqin asystematicreviewoftreatmentoutcomepredictorsindeepbrainstimulationforrefractoryobsessivecompulsivedisorder AT tonggeya asystematicreviewoftreatmentoutcomepredictorsindeepbrainstimulationforrefractoryobsessivecompulsivedisorder AT wangzhen asystematicreviewoftreatmentoutcomepredictorsindeepbrainstimulationforrefractoryobsessivecompulsivedisorder AT ruanhanyang systematicreviewoftreatmentoutcomepredictorsindeepbrainstimulationforrefractoryobsessivecompulsivedisorder AT wangyang systematicreviewoftreatmentoutcomepredictorsindeepbrainstimulationforrefractoryobsessivecompulsivedisorder AT lizheqin systematicreviewoftreatmentoutcomepredictorsindeepbrainstimulationforrefractoryobsessivecompulsivedisorder AT tonggeya systematicreviewoftreatmentoutcomepredictorsindeepbrainstimulationforrefractoryobsessivecompulsivedisorder AT wangzhen systematicreviewoftreatmentoutcomepredictorsindeepbrainstimulationforrefractoryobsessivecompulsivedisorder |