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Specific Irreversible Cell-Cycle Arrest and Depletion of Cancer Cells Obtained by Combining Curcumin and the Flavonoids Quercetin and Fisetin
Background: Induced senescence could be exploited to selectively counteract the proliferation of cancer cells and target them for senolysis. We examined the cellular senescence induced by curcumin and whether it could be targeted by fisetin and quercetin, flavonoids with senolytic activity. Methods:...
Autores principales: | Barra, Viviana, Chiavetta, Roberta Flavia, Titoli, Simona, Provenzano, Ivana Maria, Carollo, Pietro Salvatore, Di Leonardo, Aldo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9316914/ https://www.ncbi.nlm.nih.gov/pubmed/35885908 http://dx.doi.org/10.3390/genes13071125 |
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