Cargando…

In-Silico Analysis of Deleterious SNPs of FGF4 Gene and Their Impacts on Protein Structure, Function and Bladder Cancer Prognosis

Dysregulation of fibroblast growth factors is linked to the pathogenesis of bladder cancer. The role of FGF1 and FGF3 is evident in bladder cancer; however, the role of FGF4 is vague. Despite being reported that FGF4 interacts with FGF1 and FGF3 in MAPK pathways, its pathogenesis and mechanism of ac...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lim, Ee Chen, Lim, Shu Wen, Tan, Kenneth JunKai, Sathiya, Maran, Cheng, Wan Hee, Lai, Kok-Song, Loh, Jiun-Yan, Yap, Wai-Sum
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9316931/ https://www.ncbi.nlm.nih.gov/pubmed/35888106 http://dx.doi.org/10.3390/life12071018

Ejemplares similares

Predicting Deleterious Non-Synonymous Single Nucleotide Polymorphisms (nsSNPs) of HRAS Gene and In Silico Evaluation of Their Structural and Functional Consequences towards Diagnosis and Prognosis of Cancer
por: Chai, Chuan-Yu, et al.
Publicado: (2022)

Functional and structural analysis of non-synonymous single nucleotide polymorphisms (nsSNPs) in the MYB oncoproteins associated with human cancer
por: Lim, Shu Wen, et al.
Publicado: (2021)

Identification of NRAS Diagnostic Biomarkers and Drug Targets for Endometrial Cancer—An Integrated in Silico Approach
por: Alessandro, Larsen, et al.
Publicado: (2022)

In silico prediction of deleterious non-synonymous SNPs in STAT3
por: Ajith, Athira, et al.
Publicado: (2023)

In-Silico Computing of the Most Deleterious nsSNPs in HBA1 Gene
por: AbdulAzeez, Sayed, et al.
Publicado: (2016)

In silico analyses of deleterious missense SNPs of human apolipoprotein E3
por: Pires, Allan S., et al.
Publicado: (2017)

miRNA in Ischemic Heart Disease and Its Potential as Biomarkers: A Comprehensive Review
por: Kong, Amanda Shen-Yee, et al.
Publicado: (2022)

Oxidative Stress Parameters as Biomarkers of Cardiovascular Disease towards the Development and Progression
por: Kong, Amanda Shen-Yee, et al.
Publicado: (2022)

A Metal-Containing NP Approach to Treat Methicillin-Resistant Staphylococcus aureus (MRSA): Prospects and Challenges
por: Yeo, Wendy Wai Yeng, et al.
Publicado: (2022)

A comprehensive in silico analysis of the deleterious nonsynonymous SNPs of human FOXP2 protein
por: Akter, Mahmuda, et al.
Publicado: (2022)

In silico analysis predicting effects of deleterious SNPs of human RASSF5 gene on its structure and functions
por: Hossain, Md. Shahadat, et al.
Publicado: (2020)

In silico analysis of deleterious SNPs of human MTUS1 gene and their impacts on subsequent protein structure and function
por: Rozario, Liza Teresa, et al.
Publicado: (2021)

Bioactive Compounds from Marine Sponges: Fundamentals and Applications
por: Varijakzhan, Disha, et al.
Publicado: (2021)

Predicting deleterious nsSNPs: an analysis of sequence and structural attributes
por: Dobson, Richard J, et al.
Publicado: (2006)

Screening and Evaluation of Deleterious SNPs in APOE Gene of Alzheimer's Disease
por: Masoodi, Tariq Ahmad, et al.
Publicado: (2012)

In silico screening and identification of deleterious missense SNPs along with their effects on CD-209 gene: An insight to CD-209 related-diseases
por: Kakar, Mohib Ullah, et al.
Publicado: (2021)

An ANN model for the identification of deleterious nsSNPs in tumor suppressor genes
por: Chandra, Vinod, et al.
Publicado: (2011)

Functional analysis of deleterious EPHA2 SNPs in lens epithelial cells
por: Li, Dan, et al.
Publicado: (2021)

Functional analysis of deleterious EPHA2 SNPs in lens epithelial cells
por: Li, Dan, et al.
Publicado: (2021)

Computational Analysis of Deleterious SNPs in NRAS to Assess Their Potential Correlation With Carcinogenesis
por: Behairy, Mohammed Y., et al.
Publicado: (2022)

Scrutinizing Deleterious Nonsynonymous SNPs and Their Effect on Human POLD1 Gene
por: Bappy, Md. Nazmul Islam, et al.
Publicado: (2022)

Predicting the most deleterious missense nsSNPs of the protein isoforms of the human HLA-G gene and in silico evaluation of their structural and functional consequences
por: Emadi, Elaheh, et al.
Publicado: (2020)

Correction: In silico screening and identification of deleterious missense SNPs along with their effects on CD-209 gene: An insight to CD-209 related-diseases
por: Kakar, Mohib Ullah, et al.
Publicado: (2022)

Current molecular approach for diagnosis of MRSA: a meta-narrative review
por: Xing, Sim Yi, et al.
Publicado: (2022)

Prediction of Deleterious Non-Synonymous SNPs Based on Protein Interaction Network and Hybrid Properties
por: Huang, Tao, et al.
Publicado: (2010)

Structure analysis of deleterious nsSNPs in human PALB2 protein for functional inference
por: Nawar, Noshin, et al.
Publicado: (2021)

Anti- and Pro-Oxidant Properties of Essential Oils against Antimicrobial Resistance
por: Kong, Amanda Shen-Yee, et al.
Publicado: (2022)

Exploration of structural stability in deleterious nsSNPs of the XPA gene: A molecular dynamics approach
por: NagaSundaram, N, et al.
Publicado: (2011)

Additivity vs. Synergism: Investigation of the Additive Interaction of Cinnamon Bark Oil and Meropenem in Combinatory Therapy
por: Yang, Shun-Kai, et al.
Publicado: (2017)

Accurate Sequence-Based Prediction of Deleterious nsSNPs with Multiple Sequence Profiles and Putative Binding Residues
por: Song, Ruiyang, et al.
Publicado: (2021)

Structural genomics approach to investigate deleterious impact of nsSNPs in conserved telomere maintenance component 1
por: Choudhury, Arunabh, et al.
Publicado: (2021)

Intestinal-derived FGF15 protects against deleterious effects of vertical sleeve gastrectomy in mice
por: Bozadjieva-Kramer, Nadejda, et al.
Publicado: (2021)

Antimicrobial activity and mode of action of terpene linalyl anthranilate against carbapenemase-producing Klebsiella pneumoniae
por: Yang, Shun-Kai, et al.
Publicado: (2021)

In silico Analysis Reveals Distribution of Quorum Sensing Genes and Consistent Presence of LuxR Solos in the Pandoraea Species
por: Chua, Kah-Ooi, et al.
Publicado: (2019)

Identification of deleterious nsSNPs in α, μ, π and θ class of GST family and their influence on protein structure
por: Yadav, P., et al.
Publicado: (2014)

Identification, analysis of deleterious SNPs of the human GSR gene and their effects on the structure and functions of associated proteins and other diseases
por: Vyas, Bharti, et al.
Publicado: (2022)

A Simulation Analysis and Screening of Deleterious Nonsynonymous Single Nucleotide Polymorphisms (nsSNPs) in Sheep LEP Gene
por: Girmay, Shishay, et al.
Publicado: (2022)

Screening of 22q11.2DS Using Multiplex Ligation-Dependent Probe Amplification as an Alternative Diagnostic Method
por: Maran, Sathiya, et al.
Publicado: (2020)

Mutations in the tail domain of MYH3 contributes to atrial septal defect
por: Maran, Sathiya, et al.
Publicado: (2020)

In silico analysis for determining the deleterious nonsynonymous single nucleotide polymorphisms of BRCA genes
por: Yadegari, Fatemeh, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_mmh20gfg0clkt4tira4j5fbe2i