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Dehydroisohispanolone as a Promising NLRP3 Inhibitor Agent: Bioevaluation and Molecular Docking
Dehydroisohispanolone (DIH), is a labdane diterpene that has exhibited anti-inflammatory activity via inhibition of NF-κB activation, although its potential effects on inflammasome activation remain unexplored. This study aims to elucidate whether DIH modulates NLR family pyrin domain-containing pro...
Autores principales: | González-Cofrade, Laura, Cuadrado, Irene, Amesty, Ángel, Estévez-Braun, Ana, de las Heras, Beatriz, Hortelano, Sonsoles |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9316970/ https://www.ncbi.nlm.nih.gov/pubmed/35890124 http://dx.doi.org/10.3390/ph15070825 |
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