Cargando…

Development of a Mucoadhesive Vehicle Based on Lyophilized Liposomes for Drug Delivery through the Sublingual Mucosa

A pharmaceutical vehicle based on lyophilized liposomes is proposed for the buccal administration of drugs aimed at systemic delivery through the sublingual mucosa. Liposomes made of egg phosphatidylcholine and cholesterol (7/3 molar ratio) were prepared and lyophilized in the presence of different...

Descripción completa

Detalles Bibliográficos
Autores principales:	De Jesús Valle, María José, Zarzuelo Castañeda, Aranzazu, Maderuelo, Cristina, Cencerrado Treviño, Alejandro, Loureiro, Jorge, Coutinho, Paula, Sánchez Navarro, Amparo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9317145/ https://www.ncbi.nlm.nih.gov/pubmed/35890395 http://dx.doi.org/10.3390/pharmaceutics14071497

Ejemplares similares

The Preparation and Evaluation of Cyanocobalamin Mucoadhesive Sublingual Tablets
por: Ma’ali, Anwar, et al.
Publicado: (2023)

Lyoprotective Effects of Mannitol and Lactose Compared to Sucrose and Trehalose: Sildenafil Citrate Liposomes as a Case Study
por: de Jesús Valle, María José, et al.
Publicado: (2021)

Mucosal Adjuvants Delivered by a Mucoadhesive Patch for Sublingual Administration of Subunit Vaccines
por: Monge, Claire, et al.
Publicado: (2022)

Lyophilized Chitosan/xanthan Polyelectrolyte Complex Based Mucoadhesive Inserts for Nasal Delivery of Promethazine Hydrochloride
por: G Dehghan, Mohamed Hassan, et al.
Publicado: (2014)

Lyophilization of Liposomal Formulations: Still Necessary, Still Challenging
por: Franzé, Silvia, et al.
Publicado: (2018)

Mucoadhesive Chitosan Delivery System with Chelidonii Herba Lyophilized Extract as a Promising Strategy for Vaginitis Treatment
por: Paczkowska, Magdalena, et al.
Publicado: (2020)

A quality by design approach for the development of lyophilized liposomes with simvastatin
por: Porfire, Alina, et al.
Publicado: (2017)

Formulation and Characterization of Sertaconazole Nitrate Mucoadhesive Liposomes for Vaginal Candidiasis
por: Abdellatif, Menna M, et al.
Publicado: (2020)

Maleimide-Decorated PEGylated Mucoadhesive Liposomes for Ocular Drug Delivery
por: Moiseev, Roman V., et al.
Publicado: (2022)

Lyophilized Polyvinylpyrrolidone Hydrogel for Culture of Human Oral Mucosa Stem Cells
por: Oliver-Urrutia, Carolina, et al.
Publicado: (2021)

Selected Physicochemical Properties of Lyophilized Hydrogel with Liposomal Fraction of Calcium Dobesilate
por: Pilch, Ewa, et al.
Publicado: (2018)

Chemical coupling of thiolated chitosan to preformed liposomes improves mucoadhesive properties
por: Gradauer, Kerstin, et al.
Publicado: (2012)

Enhanced efficacy of sublingual immunotherapy by liposome-mediated delivery of allergen
por: Aliu, Have, et al.
Publicado: (2017)

Effective mucoadhesive liposomal delivery system for risedronate: preparation and in vitro/in vivo characterization
por: Jung, Il-Woo, et al.
Publicado: (2014)

The Vaginal-PVPA: A Vaginal Mucosa-Mimicking In Vitro Permeation Tool for Evaluation of Mucoadhesive Formulations
por: Falavigna, Margherita, et al.
Publicado: (2020)

Mucosa-Associated Lymphoid Tissue Lymphoma of the Sublingual Salivary Gland: A Case Report
por: Aleksiejūnaitė, Monika, et al.
Publicado: (2023)

Improvement of Resveratrol Permeation through Sublingual Mucosa: Chemical Permeation Enhancers versus Spray Drying Technique to Obtain Fast-Disintegrating Sublingual Mini-Tablets
por: Di Prima, Giulia, et al.
Publicado: (2021)

Preparation of Glycyrrhetinic Acid Liposomes Using Lyophilization Monophase Solution Method: Preformulation, Optimization, and In Vitro Evaluation
por: Liu, Tingting, et al.
Publicado: (2018)

Development and Comparative In Vitro and In Vivo Study of BNN27 Mucoadhesive Liposomes and Nanoemulsions for Nose-to-Brain Delivery
por: Kannavou, Maria, et al.
Publicado: (2023)

Development and Evaluation of a Novel Mucoadhesive Film Containing Acmella oleracea Extract for Oral Mucosa Topical Anesthesia
por: Santana de Freitas-Blanco, Verônica, et al.
Publicado: (2016)

Peptide KSL-W-Loaded Mucoadhesive Liquid Crystalline Vehicle as an Alternative Treatment for Multispecies Oral Biofilm
por: Bernegossi, Jéssica, et al.
Publicado: (2015)

Development of lyophilization cycle and effect of excipients on the stability of catalase during lyophilization
por: Lale, Shantanu V, et al.
Publicado: (2011)

Mucoadhesive Rifampicin-Liposomes for the Treatment of Pulmonary Infection by Mycobacterium abscessus: Chitosan or ε-Poly-L-Lysine Decoration
por: Forte, Jacopo, et al.
Publicado: (2023)

Conventional and PEGylated Liposomes as Vehicles of Copaifera sabulicola
por: Blanco, Ian M. R., et al.
Publicado: (2023)

Mucoadhesive Marine Polysaccharides
por: Yermak, Irina M., et al.
Publicado: (2022)

An application of sublingual mucosa to establish a new urination passage in male cats with complications after urethrostomy
por: YIPPADITR, Wanchart, et al.
Publicado: (2019)

Lyophilized, thermostable Spike or RBD immunogenic liposomes induce protective immunity against SARS-CoV-2 in mice
por: Mabrouk, Moustafa T., et al.
Publicado: (2021)

Paramagnetic changes in cancer: DMBA-induced tumours studied in non-lyophilized and lyophilized tissues.
por: Gutierrez, P. L., et al.
Publicado: (1979)

Mucoadhesive Gelatin Buccal Films with Propranolol Hydrochloride: Evaluation of Mechanical, Mucoadhesive, and Biopharmaceutical Properties
por: Jovanović, Marija, et al.
Publicado: (2021)

Comparative analysis of the oral mucosae from rodents and non-rodents: Application to the nonclinical evaluation of sublingual immunotherapy products
por: Thirion-Delalande, Catherine, et al.
Publicado: (2017)

ESR signals of lyophilized tissue.
por: Dodd, N. J., et al.
Publicado: (1980)

The Lyophilic Colloids (Their Theory and Practice)
por: Coghill, Robert D.
Publicado: (1934)

Lyophilic Colloids: Their Theory and Practice
Publicado: (1934)

Lyophilization Based Isolation of Exosomes
por: Qazi, Rida e Maria, et al.
Publicado: (2023)

Mucoadhesive drug delivery systems
por: Shaikh, Rahamatullah, et al.
Publicado: (2011)

Mucoadhesive Electrospun Patch Delivery of Lidocaine to the Oral Mucosa and Investigation of Spatial Distribution in a Tissue Using MALDI-Mass Spectrometry Imaging
por: Clitherow, Katharina H., et al.
Publicado: (2019)

Enhancing Stability and Mucoadhesive Properties of Chitosan Nanoparticles by Surface Modification with Sodium Alginate and Polyethylene Glycol for Potential Oral Mucosa Vaccine Delivery
por: Amin, Muhammad Khairul, et al.
Publicado: (2022)

Iontosomes: Electroresponsive Liposomes for Topical Iontophoretic Delivery of Chemotherapeutics to the Buccal Mucosa
por: Sonaje, Kiran, et al.
Publicado: (2021)

Microbubble–liposome conjugate: Payload evaluation of potential theranostic vehicle
por: Malik, Ritu, et al.
Publicado: (2016)

Bioavailability by design — Vitamin D(3) liposomal delivery vehicles
por: Dałek, Paulina, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_oqob5un8orekkhn8hcg2vim0kb