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Randomised Controlled Trial of Fish Oil Supplementation on Responsiveness to Resistance Exercise Training in Sarcopenic Older Women

This study aims to investigate the effects of fish oil supplementation on the muscle adaptive response to resistance exercise training, physical performance and serum levels of inflammatory cytokines in sarcopenic older women. A randomised, double-blind, placebo-controlled trial is performed with th...

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Autores principales: da Cruz Alves, Natália Maira, Pfrimer, Karina, Santos, Priscila Carvalho, de Freitas, Ellen Cristini, Neves, Thiago, Pessini, Rodrigo Antônio, Junqueira-Franco, Márcia Varella Morandi, Nogueira-Barbosa, Marcello H., Greig, Carolyn Anne, Ferriolli, Eduardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9317261/
https://www.ncbi.nlm.nih.gov/pubmed/35889801
http://dx.doi.org/10.3390/nu14142844
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author da Cruz Alves, Natália Maira
Pfrimer, Karina
Santos, Priscila Carvalho
de Freitas, Ellen Cristini
Neves, Thiago
Pessini, Rodrigo Antônio
Junqueira-Franco, Márcia Varella Morandi
Nogueira-Barbosa, Marcello H.
Greig, Carolyn Anne
Ferriolli, Eduardo
author_facet da Cruz Alves, Natália Maira
Pfrimer, Karina
Santos, Priscila Carvalho
de Freitas, Ellen Cristini
Neves, Thiago
Pessini, Rodrigo Antônio
Junqueira-Franco, Márcia Varella Morandi
Nogueira-Barbosa, Marcello H.
Greig, Carolyn Anne
Ferriolli, Eduardo
author_sort da Cruz Alves, Natália Maira
collection PubMed
description This study aims to investigate the effects of fish oil supplementation on the muscle adaptive response to resistance exercise training, physical performance and serum levels of inflammatory cytokines in sarcopenic older women. A randomised, double-blind, placebo-controlled trial is performed with thirty-four sarcopenic women (2010 European Consensus of Sarcopenia), aged ≥ 65 years. The participants are allocated into the following two groups: Exercise and Fish Oil (EFO) and Exercise and Placebo (EP). Both groups undertook a resistance exercise programme over 14 weeks. All participants are instructed to ingest 4 g/day of food supplements; the EP group received sunflower oil capsules, and the EFO group, fish oil capsules. The cross-sectional area (CSA) of the quadriceps muscle is calculated using magnetic resonance imaging (MRI). The strength of the lower limbs is measured using isokinetic dynamometry. Both groups show improvements in CSA and strength after the intervention. Changes in EFO are significantly greater compared with EP for muscle strength (peak torque, 19.46 Nm and 5.74 Nm, respectively, p < 0.001). CSA increased after the intervention in both groups (EFO; 6.11% and EP; 2.91%), although there is no significant difference between the groups (p = 0.23). There are no significant intra-group, inter-group or time differences in any of the cytokines measured. The use of fish oil supplementation potentiates the neuromuscular response to the anabolic stimulus from training, increasing muscle strength and physical performance in sarcopenic older women.
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spelling pubmed-93172612022-07-27 Randomised Controlled Trial of Fish Oil Supplementation on Responsiveness to Resistance Exercise Training in Sarcopenic Older Women da Cruz Alves, Natália Maira Pfrimer, Karina Santos, Priscila Carvalho de Freitas, Ellen Cristini Neves, Thiago Pessini, Rodrigo Antônio Junqueira-Franco, Márcia Varella Morandi Nogueira-Barbosa, Marcello H. Greig, Carolyn Anne Ferriolli, Eduardo Nutrients Article This study aims to investigate the effects of fish oil supplementation on the muscle adaptive response to resistance exercise training, physical performance and serum levels of inflammatory cytokines in sarcopenic older women. A randomised, double-blind, placebo-controlled trial is performed with thirty-four sarcopenic women (2010 European Consensus of Sarcopenia), aged ≥ 65 years. The participants are allocated into the following two groups: Exercise and Fish Oil (EFO) and Exercise and Placebo (EP). Both groups undertook a resistance exercise programme over 14 weeks. All participants are instructed to ingest 4 g/day of food supplements; the EP group received sunflower oil capsules, and the EFO group, fish oil capsules. The cross-sectional area (CSA) of the quadriceps muscle is calculated using magnetic resonance imaging (MRI). The strength of the lower limbs is measured using isokinetic dynamometry. Both groups show improvements in CSA and strength after the intervention. Changes in EFO are significantly greater compared with EP for muscle strength (peak torque, 19.46 Nm and 5.74 Nm, respectively, p < 0.001). CSA increased after the intervention in both groups (EFO; 6.11% and EP; 2.91%), although there is no significant difference between the groups (p = 0.23). There are no significant intra-group, inter-group or time differences in any of the cytokines measured. The use of fish oil supplementation potentiates the neuromuscular response to the anabolic stimulus from training, increasing muscle strength and physical performance in sarcopenic older women. MDPI 2022-07-11 /pmc/articles/PMC9317261/ /pubmed/35889801 http://dx.doi.org/10.3390/nu14142844 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
da Cruz Alves, Natália Maira
Pfrimer, Karina
Santos, Priscila Carvalho
de Freitas, Ellen Cristini
Neves, Thiago
Pessini, Rodrigo Antônio
Junqueira-Franco, Márcia Varella Morandi
Nogueira-Barbosa, Marcello H.
Greig, Carolyn Anne
Ferriolli, Eduardo
Randomised Controlled Trial of Fish Oil Supplementation on Responsiveness to Resistance Exercise Training in Sarcopenic Older Women
title Randomised Controlled Trial of Fish Oil Supplementation on Responsiveness to Resistance Exercise Training in Sarcopenic Older Women
title_full Randomised Controlled Trial of Fish Oil Supplementation on Responsiveness to Resistance Exercise Training in Sarcopenic Older Women
title_fullStr Randomised Controlled Trial of Fish Oil Supplementation on Responsiveness to Resistance Exercise Training in Sarcopenic Older Women
title_full_unstemmed Randomised Controlled Trial of Fish Oil Supplementation on Responsiveness to Resistance Exercise Training in Sarcopenic Older Women
title_short Randomised Controlled Trial of Fish Oil Supplementation on Responsiveness to Resistance Exercise Training in Sarcopenic Older Women
title_sort randomised controlled trial of fish oil supplementation on responsiveness to resistance exercise training in sarcopenic older women
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9317261/
https://www.ncbi.nlm.nih.gov/pubmed/35889801
http://dx.doi.org/10.3390/nu14142844
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