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Efficient Identification of the MYC Regulator with the Use of the CRISPR Library and Context-Matched Database Screenings

MYC is a major oncogene that plays an important role in cell proliferation in human cancers. Therefore, the mechanism behind MYC regulation is a viable therapeutic target for the treatment of cancer. Comprehensive and efficient screening of MYC regulators is needed, and we had previously established...

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Detalles Bibliográficos
Autores principales: Tanaka, Yosuke, Kambayashi, Hidetaka, Yamamoto, Akiko, Onishi, Iichiroh, Sugita, Keisuke, Matsumura, Miwa, Ishibashi, Sachiko, Ikeda, Masumi, Yamamoto, Kouhei, Kitagawa, Masanobu, Kurata, Morito
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9317319/
https://www.ncbi.nlm.nih.gov/pubmed/35887071
http://dx.doi.org/10.3390/ijms23147723