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Pro-cancerogenic effects of spontaneous and drug-induced senescence of ovarian cancer cells in vitro and in vivo: a comparative analysis
BACKGROUND: Clinical outcomes of cancer cell senescence are still elusive. Here, we reveal and compare pro-cancerous activity of spontaneously and drug-inducible senescent ovarian cancer cells. Experiments were performed on tumors and tumor-derived primary epithelial ovarian cancer cells (pEOCs) tha...
Autores principales: | Rutecki, Szymon, Szulc, Paulina, Pakuła, Martyna, Uruski, Paweł, Radziemski, Artur, Naumowicz, Eryk, Moszyński, Rafał, Tykarski, Andrzej, Mikuła-Pietrasik, Justyna, Książek, Krzysztof |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9317468/ https://www.ncbi.nlm.nih.gov/pubmed/35883110 http://dx.doi.org/10.1186/s13048-022-01023-y |
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