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Pro-cancerogenic effects of spontaneous and drug-induced senescence of ovarian cancer cells in vitro and in vivo: a comparative analysis

BACKGROUND: Clinical outcomes of cancer cell senescence are still elusive. Here, we reveal and compare pro-cancerous activity of spontaneously and drug-inducible senescent ovarian cancer cells. Experiments were performed on tumors and tumor-derived primary epithelial ovarian cancer cells (pEOCs) tha...

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Detalles Bibliográficos
Autores principales: Rutecki, Szymon, Szulc, Paulina, Pakuła, Martyna, Uruski, Paweł, Radziemski, Artur, Naumowicz, Eryk, Moszyński, Rafał, Tykarski, Andrzej, Mikuła-Pietrasik, Justyna, Książek, Krzysztof
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9317468/
https://www.ncbi.nlm.nih.gov/pubmed/35883110
http://dx.doi.org/10.1186/s13048-022-01023-y

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