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The Role of Resveratrol in Eye Diseases—A Review of the Literature

Resveratrol (3,5,4′-trans-trihydroxystilbene) is a polyphenolic phytoalexin belonging to the stilbene family. It is commonly found in grape skins and seeds, as well as other plant-based foods. Oxidative stress and inflammation play a key role in the initiation and progression of age-related eye diso...

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Autores principales: Bryl, Anna, Falkowski, Mariusz, Zorena, Katarzyna, Mrugacz, Małgorzata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9317487/
https://www.ncbi.nlm.nih.gov/pubmed/35889930
http://dx.doi.org/10.3390/nu14142974
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author Bryl, Anna
Falkowski, Mariusz
Zorena, Katarzyna
Mrugacz, Małgorzata
author_facet Bryl, Anna
Falkowski, Mariusz
Zorena, Katarzyna
Mrugacz, Małgorzata
author_sort Bryl, Anna
collection PubMed
description Resveratrol (3,5,4′-trans-trihydroxystilbene) is a polyphenolic phytoalexin belonging to the stilbene family. It is commonly found in grape skins and seeds, as well as other plant-based foods. Oxidative stress and inflammation play a key role in the initiation and progression of age-related eye disorders (glaucoma, cataracts, diabetic retinopathy, and macular degeneration) that lead to a progressive loss of vision and blindness. Even though the way resveratrol affects the human body and the course of many diseases is still the subject of ongoing scientific research, it has been shown that the broad spectrum of anti-inflammatory and neuroprotective properties of resveratrol has a beneficial effect on eye tissues. In our research, we decided to analyze the current scientific literature on resveratrol, its possible mechanisms of action, and its therapeutic application in order to assess its effectiveness in eye diseases.
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spelling pubmed-93174872022-07-27 The Role of Resveratrol in Eye Diseases—A Review of the Literature Bryl, Anna Falkowski, Mariusz Zorena, Katarzyna Mrugacz, Małgorzata Nutrients Review Resveratrol (3,5,4′-trans-trihydroxystilbene) is a polyphenolic phytoalexin belonging to the stilbene family. It is commonly found in grape skins and seeds, as well as other plant-based foods. Oxidative stress and inflammation play a key role in the initiation and progression of age-related eye disorders (glaucoma, cataracts, diabetic retinopathy, and macular degeneration) that lead to a progressive loss of vision and blindness. Even though the way resveratrol affects the human body and the course of many diseases is still the subject of ongoing scientific research, it has been shown that the broad spectrum of anti-inflammatory and neuroprotective properties of resveratrol has a beneficial effect on eye tissues. In our research, we decided to analyze the current scientific literature on resveratrol, its possible mechanisms of action, and its therapeutic application in order to assess its effectiveness in eye diseases. MDPI 2022-07-20 /pmc/articles/PMC9317487/ /pubmed/35889930 http://dx.doi.org/10.3390/nu14142974 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Bryl, Anna
Falkowski, Mariusz
Zorena, Katarzyna
Mrugacz, Małgorzata
The Role of Resveratrol in Eye Diseases—A Review of the Literature
title The Role of Resveratrol in Eye Diseases—A Review of the Literature
title_full The Role of Resveratrol in Eye Diseases—A Review of the Literature
title_fullStr The Role of Resveratrol in Eye Diseases—A Review of the Literature
title_full_unstemmed The Role of Resveratrol in Eye Diseases—A Review of the Literature
title_short The Role of Resveratrol in Eye Diseases—A Review of the Literature
title_sort role of resveratrol in eye diseases—a review of the literature
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9317487/
https://www.ncbi.nlm.nih.gov/pubmed/35889930
http://dx.doi.org/10.3390/nu14142974
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