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The Role of Resveratrol in Eye Diseases—A Review of the Literature
Resveratrol (3,5,4′-trans-trihydroxystilbene) is a polyphenolic phytoalexin belonging to the stilbene family. It is commonly found in grape skins and seeds, as well as other plant-based foods. Oxidative stress and inflammation play a key role in the initiation and progression of age-related eye diso...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9317487/ https://www.ncbi.nlm.nih.gov/pubmed/35889930 http://dx.doi.org/10.3390/nu14142974 |
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author | Bryl, Anna Falkowski, Mariusz Zorena, Katarzyna Mrugacz, Małgorzata |
author_facet | Bryl, Anna Falkowski, Mariusz Zorena, Katarzyna Mrugacz, Małgorzata |
author_sort | Bryl, Anna |
collection | PubMed |
description | Resveratrol (3,5,4′-trans-trihydroxystilbene) is a polyphenolic phytoalexin belonging to the stilbene family. It is commonly found in grape skins and seeds, as well as other plant-based foods. Oxidative stress and inflammation play a key role in the initiation and progression of age-related eye disorders (glaucoma, cataracts, diabetic retinopathy, and macular degeneration) that lead to a progressive loss of vision and blindness. Even though the way resveratrol affects the human body and the course of many diseases is still the subject of ongoing scientific research, it has been shown that the broad spectrum of anti-inflammatory and neuroprotective properties of resveratrol has a beneficial effect on eye tissues. In our research, we decided to analyze the current scientific literature on resveratrol, its possible mechanisms of action, and its therapeutic application in order to assess its effectiveness in eye diseases. |
format | Online Article Text |
id | pubmed-9317487 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-93174872022-07-27 The Role of Resveratrol in Eye Diseases—A Review of the Literature Bryl, Anna Falkowski, Mariusz Zorena, Katarzyna Mrugacz, Małgorzata Nutrients Review Resveratrol (3,5,4′-trans-trihydroxystilbene) is a polyphenolic phytoalexin belonging to the stilbene family. It is commonly found in grape skins and seeds, as well as other plant-based foods. Oxidative stress and inflammation play a key role in the initiation and progression of age-related eye disorders (glaucoma, cataracts, diabetic retinopathy, and macular degeneration) that lead to a progressive loss of vision and blindness. Even though the way resveratrol affects the human body and the course of many diseases is still the subject of ongoing scientific research, it has been shown that the broad spectrum of anti-inflammatory and neuroprotective properties of resveratrol has a beneficial effect on eye tissues. In our research, we decided to analyze the current scientific literature on resveratrol, its possible mechanisms of action, and its therapeutic application in order to assess its effectiveness in eye diseases. MDPI 2022-07-20 /pmc/articles/PMC9317487/ /pubmed/35889930 http://dx.doi.org/10.3390/nu14142974 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Bryl, Anna Falkowski, Mariusz Zorena, Katarzyna Mrugacz, Małgorzata The Role of Resveratrol in Eye Diseases—A Review of the Literature |
title | The Role of Resveratrol in Eye Diseases—A Review of the Literature |
title_full | The Role of Resveratrol in Eye Diseases—A Review of the Literature |
title_fullStr | The Role of Resveratrol in Eye Diseases—A Review of the Literature |
title_full_unstemmed | The Role of Resveratrol in Eye Diseases—A Review of the Literature |
title_short | The Role of Resveratrol in Eye Diseases—A Review of the Literature |
title_sort | role of resveratrol in eye diseases—a review of the literature |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9317487/ https://www.ncbi.nlm.nih.gov/pubmed/35889930 http://dx.doi.org/10.3390/nu14142974 |
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