The Intracellular Distribution of the Small GTPase Rho5 and Its Dimeric Guanidine Nucleotide Exchange Factor Dck1/Lmo1 Determine Their Function in Oxidative Stress Response

Rho5, the yeast homolog of human Rac1, is a small GTPase which regulates the cell response to nutrient and oxidative stress by inducing mitophagy and apoptosis. It is activated by a dimeric GEF composed of the subunits Dck1 and Lmo1. Upon stress, all three proteins rapidly translocate from the cell...

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Detalles Bibliográficos
Autores principales: Bischof, Linnet, Schweitzer, Franziska, Sterk, Carolin C., Heinisch, Jürgen J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9317549/
https://www.ncbi.nlm.nih.gov/pubmed/35887245
http://dx.doi.org/10.3390/ijms23147896

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9317549/
https://www.ncbi.nlm.nih.gov/pubmed/35887245
http://dx.doi.org/10.3390/ijms23147896

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