Cargando…

Human Beta Papillomavirus Type 8 E1 and E2 Proteins Suppress the Activation of the RIG-I-Like Receptor MDA5

Persistent infections of the skin with the human papillomavirus of genus beta (β-HPV) in immunocompetent individuals are asymptomatic, but in immunosuppressed patients, β-HPV infections exhibit much higher viral loads on the skin and are associated with an increased risk of skin cancer. Unlike with...

Descripción completa

Detalles Bibliográficos
Autores principales:	Rattay, Stephanie, Hufbauer, Martin, Hagen, Christian, Putschli, Bastian, Coch, Christoph, Akgül, Baki, Hartmann, Gunther
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9317666/ https://www.ncbi.nlm.nih.gov/pubmed/35891343 http://dx.doi.org/10.3390/v14071361

Ejemplares similares

Molecular Mechanisms of Human Papillomavirus Induced Skin Carcinogenesis
por: Hufbauer, Martin, et al.
Publicado: (2017)

The Protein Tyrosine Phosphatase H1 PTPH1 Supports Proliferation of Keratinocytes and is a Target of the Human Papillomavirus Type 8 E6 Oncogene
por: Taute, Stefanie, et al.
Publicado: (2019)

Phospholipidation of nuclear proteins by the human papillomavirus E6 oncoprotein: implication in carcinogenesis
por: Marx, Benjamin, et al.
Publicado: (2018)

RIG-I activation induces the release of extracellular vesicles with antitumor activity
por: Daßler-Plenker, Juliane, et al.
Publicado: (2016)

Inactivation of Polyomavirus SV40 as Surrogate for Human Papillomaviruses by Chemical Disinfectants
por: Hufbauer, Martin, et al.
Publicado: (2021)

A Human In Vitro Whole Blood Assay to Predict the Systemic Cytokine Response to Therapeutic Oligonucleotides Including siRNA
por: Coch, Christoph, et al.
Publicado: (2013)

HPV8-E6 Interferes with Syntenin-2 Expression through Deregulation of Differentiation, Methylation and Phosphatidylinositide-Kinase Dependent Mechanisms
por: Marx, Benjamin, et al.
Publicado: (2017)

Two-factor Oncogenesis in a Human Papillomavirus 68-associated Penile Carcinoma
por: KREUTER, Alexander, et al.
Publicado: (2021)

Novel Insights Into Cellular Changes in HPV8-E7 Positive Keratinocytes: A Transcriptomic and Proteomic Analysis
por: Kirschberg, Matthias, et al.
Publicado: (2021)

Human papillomavirus mediated inhibition of DNA damage sensing and repair drives skin carcinogenesis
por: Hufbauer, Martin, et al.
Publicado: (2015)

Comparative Structure and Function Analysis of the RIG-I-Like Receptors: RIG-I and MDA5
por: Brisse, Morgan, et al.
Publicado: (2019)

Human TLR8 Senses RNA From Plasmodium falciparum-Infected Red Blood Cells Which Is Uniquely Required for the IFN-γ Response in NK Cells
por: Coch, Christoph, et al.
Publicado: (2019)

Pattern Recognition and Signaling Mechanisms of RIG-I and MDA5
por: Reikine, Stephanie, et al.
Publicado: (2014)

Beta human papillomavirus 8E6 promotes alternative end joining
por: Hu, Changkun, et al.
Publicado: (2023)

HPV8 Reverses the Transcriptional Output in Lrig1 Positive Cells to Drive Skin Tumorigenesis
por: Syed, Adnan Shahzad, et al.
Publicado: (2022)

RIG-I Detects Triphosphorylated RNA of Listeria monocytogenes during Infection in Non-Immune Cells
por: Hagmann, Cristina Amparo, et al.
Publicado: (2013)

Analysis of Porcine RIG-I Like Receptors Revealed the Positive Regulation of RIG-I and MDA5 by LGP2
por: Li, Shuangjie, et al.
Publicado: (2021)

A conserved isoleucine in the binding pocket of RIG-I controls immune tolerance to mitochondrial RNA
por: de Regt, Ann Kristin, et al.
Publicado: (2023)

The Ubiquitin E3 Ligase Parkin Inhibits Innate Antiviral Immunity Through K48-Linked Polyubiquitination of RIG-I and MDA5
por: Bu, Lang, et al.
Publicado: (2020)

In Vivo Ligands of MDA5 and RIG-I in Measles Virus-Infected Cells
por: Runge, Simon, et al.
Publicado: (2014)

Therapeutic Targeting of RIG-I and MDA5 Might Not Lead to the Same Rome
por: Kasumba, Dacquin M., et al.
Publicado: (2019)

The E3 ligase Riplet promotes RIG-I signaling independent of RIG-I oligomerization
por: Wang, Wenshuai, et al.
Publicado: (2023)

Human Hemoglobin Subunit Beta Functions as a Pleiotropic Regulator of RIG-I/MDA5-Mediated Antiviral Innate Immune Responses
por: Yang, Qian, et al.
Publicado: (2019)

Transforming Properties of Beta-3 Human Papillomavirus E6 and E7 Proteins
por: Minoni, Lucia, et al.
Publicado: (2020)

Monocyte-dependent co-stimulation of cytokine induction in human γδ T cells by TLR8 RNA ligands
por: Serrano, Ruben, et al.
Publicado: (2021)

Functions of Papillomavirus E8^E2 Proteins in Tissue Culture and In Vivo
por: Kuehner, Franziska, et al.
Publicado: (2022)

Beta-Genus Human Papillomavirus 8 E6 Destabilizes the Host Genome by Promoting p300 Degradation
por: Dacus, Dalton, et al.
Publicado: (2021)

Kinetic discrimination of self/non-self RNA by the ATPase activity of RIG-I and MDA5
por: Louber, Jade, et al.
Publicado: (2015)

Innate immunity to RNA virus is regulated by temporal and reversible sumoylation of RIG-I and MDA5
por: Hu, Ming-Ming, et al.
Publicado: (2017)

ZFYVE1 negatively regulates MDA5- but not RIG-I-mediated innate antiviral response
por: Zhong, Xuan, et al.
Publicado: (2020)

Expression of a Functional Mx1 Protein Is Essential for the Ability of RIG-I Agonist Prophylaxis to Provide Potent and Long-Lasting Protection in a Mouse Model of Influenza A Virus Infection
por: Schwab, Lara S. U., et al.
Publicado: (2022)

Induction of Tyrosine Phosphorylation of UV-Activated EGFR by the Beta-Human Papillomavirus Type 8 E6 Leads to Papillomatosis
por: Taute, Stefanie, et al.
Publicado: (2017)

Beta Human Papillomavirus 8E6 Attenuates Non-Homologous End Joining by Hindering DNA-PKcs Activity
por: Hu, Changkun, et al.
Publicado: (2020)

Cutaneous Human Papillomavirus E7 Type-Specific Effects on Differentiation and Proliferation of Organotypic Skin Cultures
por: Westphal, K., et al.
Publicado: (2009)

Beta-Carotene, Vitamin E, MDA, Glutathione Reductase and Arylesterase Activity Levels in Patients with Active Rheumatoid Arthritis
por: Aryaeian, N, et al.
Publicado: (2011)

Bovine Delta Papillomavirus E5 Oncoprotein Interacts With TRIM25 and Hampers Antiviral Innate Immune Response Mediated by RIG-I-Like Receptors
por: De Falco, Francesca, et al.
Publicado: (2021)

Beta human papillomavirus 8 E6 allows colocalization of non-homologous end joining and homologous recombination repair factors
por: Hu, Changkun, et al.
Publicado: (2022)

Induction of Innate Immune Responses by SIV In Vivo and In Vitro: Differential Expression and Function of RIG-I and MDA5
por: Co, Juliene G., et al.
Publicado: (2011)

RIG-I, MDA5 and TLR3 Synergistically Play an Important Role in Restriction of Dengue Virus Infection
por: Nasirudeen, A. M. A., et al.
Publicado: (2011)

Co-ordinated Role of TLR3, RIG-I and MDA5 in the Innate Response to Rhinovirus in Bronchial Epithelium
por: Slater, Louise, et al.
Publicado: (2010)

Cannot write session to /tmp/vufind_sessions/sess_dcv4sh1kk9u587d7h00jtf2ns3