Cargando…

The Gut Microbiota of Obese Children Releases Lower Antioxidant Capacity from Food than That of Lean Children

The prevalence of obesity has been increasing in children over the last few decades, becoming a concern for health professionals and governments. Gut microbial community structure in obese people have been found to differ from that of lean subjects for some taxa which could result in different produ...

Descripción completa

Detalles Bibliográficos
Autores principales: Navajas-Porras, Beatriz, Pérez-Burillo, Sergio, Hinojosa-Nogueira, Daniel, Douros, Konstantinos, Pastoriza, Silvia, Rufián-Henares, José Ángel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9317750/
https://www.ncbi.nlm.nih.gov/pubmed/35889785
http://dx.doi.org/10.3390/nu14142829
_version_ 1784755132759539712
author Navajas-Porras, Beatriz
Pérez-Burillo, Sergio
Hinojosa-Nogueira, Daniel
Douros, Konstantinos
Pastoriza, Silvia
Rufián-Henares, José Ángel
author_facet Navajas-Porras, Beatriz
Pérez-Burillo, Sergio
Hinojosa-Nogueira, Daniel
Douros, Konstantinos
Pastoriza, Silvia
Rufián-Henares, José Ángel
author_sort Navajas-Porras, Beatriz
collection PubMed
description The prevalence of obesity has been increasing in children over the last few decades, becoming a concern for health professionals and governments. Gut microbial community structure in obese people have been found to differ from that of lean subjects for some taxa which could result in different production of microbial metabolites. The aim of the present work was to study whether the gut microbiota from obese children extracts a different concentration of antioxidant capacity than the gut microbiota from lean children. For this purpose, different foods were in vitro digested and in vitro fermented using fecal material from obese and lean children. FRAP, DPPH and Folin-Ciocalteu methods were used to measure the antioxidant capacity released during digestion and fermentation. Overall, when using lean gut microbiota, antioxidant capacity released was higher when measured via DPPH and FRAP. Moreover, according to DPPH results, lean gut microbiota could potentially release more antioxidant power from vegetables than from animal products, while obese gut microbiota did the opposite. On the contrary, with the FRAP method obese gut microbiota released higher levels of antioxidant power from plant products than from animal products, but the final antioxidant capacity was still lower than that released by lean gut microbiota. Therefore, these results reflect that the total antioxidant capacity of foods is influenced by the gut microbiota, although whether that antioxidant capacity is released from plant or animal products can be slightly influenced by the method used for analysis.
format Online
Article
Text
id pubmed-9317750
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-93177502022-07-27 The Gut Microbiota of Obese Children Releases Lower Antioxidant Capacity from Food than That of Lean Children Navajas-Porras, Beatriz Pérez-Burillo, Sergio Hinojosa-Nogueira, Daniel Douros, Konstantinos Pastoriza, Silvia Rufián-Henares, José Ángel Nutrients Article The prevalence of obesity has been increasing in children over the last few decades, becoming a concern for health professionals and governments. Gut microbial community structure in obese people have been found to differ from that of lean subjects for some taxa which could result in different production of microbial metabolites. The aim of the present work was to study whether the gut microbiota from obese children extracts a different concentration of antioxidant capacity than the gut microbiota from lean children. For this purpose, different foods were in vitro digested and in vitro fermented using fecal material from obese and lean children. FRAP, DPPH and Folin-Ciocalteu methods were used to measure the antioxidant capacity released during digestion and fermentation. Overall, when using lean gut microbiota, antioxidant capacity released was higher when measured via DPPH and FRAP. Moreover, according to DPPH results, lean gut microbiota could potentially release more antioxidant power from vegetables than from animal products, while obese gut microbiota did the opposite. On the contrary, with the FRAP method obese gut microbiota released higher levels of antioxidant power from plant products than from animal products, but the final antioxidant capacity was still lower than that released by lean gut microbiota. Therefore, these results reflect that the total antioxidant capacity of foods is influenced by the gut microbiota, although whether that antioxidant capacity is released from plant or animal products can be slightly influenced by the method used for analysis. MDPI 2022-07-09 /pmc/articles/PMC9317750/ /pubmed/35889785 http://dx.doi.org/10.3390/nu14142829 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Navajas-Porras, Beatriz
Pérez-Burillo, Sergio
Hinojosa-Nogueira, Daniel
Douros, Konstantinos
Pastoriza, Silvia
Rufián-Henares, José Ángel
The Gut Microbiota of Obese Children Releases Lower Antioxidant Capacity from Food than That of Lean Children
title The Gut Microbiota of Obese Children Releases Lower Antioxidant Capacity from Food than That of Lean Children
title_full The Gut Microbiota of Obese Children Releases Lower Antioxidant Capacity from Food than That of Lean Children
title_fullStr The Gut Microbiota of Obese Children Releases Lower Antioxidant Capacity from Food than That of Lean Children
title_full_unstemmed The Gut Microbiota of Obese Children Releases Lower Antioxidant Capacity from Food than That of Lean Children
title_short The Gut Microbiota of Obese Children Releases Lower Antioxidant Capacity from Food than That of Lean Children
title_sort gut microbiota of obese children releases lower antioxidant capacity from food than that of lean children
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9317750/
https://www.ncbi.nlm.nih.gov/pubmed/35889785
http://dx.doi.org/10.3390/nu14142829
work_keys_str_mv AT navajasporrasbeatriz thegutmicrobiotaofobesechildrenreleaseslowerantioxidantcapacityfromfoodthanthatofleanchildren
AT perezburillosergio thegutmicrobiotaofobesechildrenreleaseslowerantioxidantcapacityfromfoodthanthatofleanchildren
AT hinojosanogueiradaniel thegutmicrobiotaofobesechildrenreleaseslowerantioxidantcapacityfromfoodthanthatofleanchildren
AT douroskonstantinos thegutmicrobiotaofobesechildrenreleaseslowerantioxidantcapacityfromfoodthanthatofleanchildren
AT pastorizasilvia thegutmicrobiotaofobesechildrenreleaseslowerantioxidantcapacityfromfoodthanthatofleanchildren
AT rufianhenaresjoseangel thegutmicrobiotaofobesechildrenreleaseslowerantioxidantcapacityfromfoodthanthatofleanchildren
AT navajasporrasbeatriz gutmicrobiotaofobesechildrenreleaseslowerantioxidantcapacityfromfoodthanthatofleanchildren
AT perezburillosergio gutmicrobiotaofobesechildrenreleaseslowerantioxidantcapacityfromfoodthanthatofleanchildren
AT hinojosanogueiradaniel gutmicrobiotaofobesechildrenreleaseslowerantioxidantcapacityfromfoodthanthatofleanchildren
AT douroskonstantinos gutmicrobiotaofobesechildrenreleaseslowerantioxidantcapacityfromfoodthanthatofleanchildren
AT pastorizasilvia gutmicrobiotaofobesechildrenreleaseslowerantioxidantcapacityfromfoodthanthatofleanchildren
AT rufianhenaresjoseangel gutmicrobiotaofobesechildrenreleaseslowerantioxidantcapacityfromfoodthanthatofleanchildren