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Preparation and Properties of Iron Nanoparticle-Based Macroporous Scaffolds for Biodegradable Implants

Fe-based scaffolds are of particular interest in the technology of biodegradable implants due to their high mechanical properties and biocompatibility. In the present work, using an electroexplosive Fe nanopowder and NaCl particles 100–200 µm in size as a porogen, scaffolds with a porosity of about...

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Autores principales: Lozhkomoev, Aleksandr S., Buyakov, Ales S., Kazantsev, Sergey O., Senkina, Elena I., Krinitcyn, Maksim G., Ivanyuk, Valeria A., Sharipova, Aliya F., Lerner, Marat I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9317871/
https://www.ncbi.nlm.nih.gov/pubmed/35888367
http://dx.doi.org/10.3390/ma15144900
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author Lozhkomoev, Aleksandr S.
Buyakov, Ales S.
Kazantsev, Sergey O.
Senkina, Elena I.
Krinitcyn, Maksim G.
Ivanyuk, Valeria A.
Sharipova, Aliya F.
Lerner, Marat I.
author_facet Lozhkomoev, Aleksandr S.
Buyakov, Ales S.
Kazantsev, Sergey O.
Senkina, Elena I.
Krinitcyn, Maksim G.
Ivanyuk, Valeria A.
Sharipova, Aliya F.
Lerner, Marat I.
author_sort Lozhkomoev, Aleksandr S.
collection PubMed
description Fe-based scaffolds are of particular interest in the technology of biodegradable implants due to their high mechanical properties and biocompatibility. In the present work, using an electroexplosive Fe nanopowder and NaCl particles 100–200 µm in size as a porogen, scaffolds with a porosity of about 70 ± 0.8% were obtained. The effect of the sintering temperature on the structure, composition, and mechanical characteristics of the scaffolds was considered. The optimum parameters of the sintering process were determined, allowing us to obtain samples characterized by plastic deformation and a yield strength of up to 16.2 MPa. The degradation of the scaffolds sintered at 1000 and 1100 °C in 0.9 wt.% NaCl solution for 28 days resulted in a decrease in their strength by 23% and 17%, respectively.
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spelling pubmed-93178712022-07-27 Preparation and Properties of Iron Nanoparticle-Based Macroporous Scaffolds for Biodegradable Implants Lozhkomoev, Aleksandr S. Buyakov, Ales S. Kazantsev, Sergey O. Senkina, Elena I. Krinitcyn, Maksim G. Ivanyuk, Valeria A. Sharipova, Aliya F. Lerner, Marat I. Materials (Basel) Article Fe-based scaffolds are of particular interest in the technology of biodegradable implants due to their high mechanical properties and biocompatibility. In the present work, using an electroexplosive Fe nanopowder and NaCl particles 100–200 µm in size as a porogen, scaffolds with a porosity of about 70 ± 0.8% were obtained. The effect of the sintering temperature on the structure, composition, and mechanical characteristics of the scaffolds was considered. The optimum parameters of the sintering process were determined, allowing us to obtain samples characterized by plastic deformation and a yield strength of up to 16.2 MPa. The degradation of the scaffolds sintered at 1000 and 1100 °C in 0.9 wt.% NaCl solution for 28 days resulted in a decrease in their strength by 23% and 17%, respectively. MDPI 2022-07-14 /pmc/articles/PMC9317871/ /pubmed/35888367 http://dx.doi.org/10.3390/ma15144900 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Lozhkomoev, Aleksandr S.
Buyakov, Ales S.
Kazantsev, Sergey O.
Senkina, Elena I.
Krinitcyn, Maksim G.
Ivanyuk, Valeria A.
Sharipova, Aliya F.
Lerner, Marat I.
Preparation and Properties of Iron Nanoparticle-Based Macroporous Scaffolds for Biodegradable Implants
title Preparation and Properties of Iron Nanoparticle-Based Macroporous Scaffolds for Biodegradable Implants
title_full Preparation and Properties of Iron Nanoparticle-Based Macroporous Scaffolds for Biodegradable Implants
title_fullStr Preparation and Properties of Iron Nanoparticle-Based Macroporous Scaffolds for Biodegradable Implants
title_full_unstemmed Preparation and Properties of Iron Nanoparticle-Based Macroporous Scaffolds for Biodegradable Implants
title_short Preparation and Properties of Iron Nanoparticle-Based Macroporous Scaffolds for Biodegradable Implants
title_sort preparation and properties of iron nanoparticle-based macroporous scaffolds for biodegradable implants
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9317871/
https://www.ncbi.nlm.nih.gov/pubmed/35888367
http://dx.doi.org/10.3390/ma15144900
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