Co-Crystal Structure-Guided Optimization of Dual-Functional Small Molecules for Improving the Peroxygenase Activity of Cytochrome P450BM3

We recently developed an artificial P450–H(2)O(2) system assisted by dual-functional small molecules (DFSMs) to modify the P450BM3 monooxygenase into its peroxygenase mode, which could be widely used for the oxidation of non-native substrates. Aiming to further improve the DFSM-facilitated P450–H(2)...

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Detalles Bibliográficos
Autores principales: Qin, Xiangquan, Jiang, Yiping, Chen, Jie, Yao, Fuquan, Zhao, Panxia, Jin, Longyi, Cong, Zhiqi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9317928/
https://www.ncbi.nlm.nih.gov/pubmed/35887253
http://dx.doi.org/10.3390/ijms23147901

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9317928/
https://www.ncbi.nlm.nih.gov/pubmed/35887253
http://dx.doi.org/10.3390/ijms23147901

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