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Indicators of the Right Ventricle Systolic and Diastolic Function 18 Months after Coronary Bypass Surgery
Objective. Right ventricular (RV) dysfunction after coronary artery bypass grafting (CABG) is associated with increased mortality and morbidity. In previous studies, the parameters of RV systolic function were mainly assessed, while the dynamics of RV diastolic function after surgery was practically...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9318021/ https://www.ncbi.nlm.nih.gov/pubmed/35887758 http://dx.doi.org/10.3390/jcm11143994 |
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author | Sumin, Alexey N. Shcheglova, Anna V. Korok, Ekaterina V. Sergeeva, Tatjana Ju. |
author_facet | Sumin, Alexey N. Shcheglova, Anna V. Korok, Ekaterina V. Sergeeva, Tatjana Ju. |
author_sort | Sumin, Alexey N. |
collection | PubMed |
description | Objective. Right ventricular (RV) dysfunction after coronary artery bypass grafting (CABG) is associated with increased mortality and morbidity. In previous studies, the parameters of RV systolic function were mainly assessed, while the dynamics of RV diastolic function after surgery was practically not studied. The aim of this study was to study the dynamics of indicators of systolic and diastolic RV function after CABG as well as to identify factors associated with their presence. Methods. The study included 160 patients who underwent CABG and 36 volunteers with no history of coronary artery disease (CAD) as a control group. Echocardiographic examination of patients was performed to assess systolic and diastolic RV dysfunction before surgery and 18 months after CABG. A level of s’t < 10 cm/sec or TAPSE < 16 mm was considered as a sign of existing RV systolic dysfunction. RV diastolic dysfunction was defined as an Et/At ratio < 0.8 or >2.1 and/or an Et/et’ ratio > 6. Results. In CAD patients 18 months after CABG, there was an increase in the frequency of the right ventricular systolic (from 7.5% to 30%, p < 0.001) and diastolic (from 41.8% to 57.5%, p < 0.001) dysfunction. An increase in TAPSE (p = 0.007), a decrease in e’t (p = 0.005), and the presence of RV systolic dysfunction before surgery (p = 0.023) was associated with a significant increase in the likelihood of detecting RV systolic dysfunction 18 months after CABG (χ(2)(3) = 17.4, p = 0.001). High values of At before surgery (p = 0.021) and old myocardial infarction (p = 0.023) were significantly associated with an increased likelihood of detection of RV diastolic dysfunction 18 months after CABG (χ(2)(2) = 10.78, p = 0.005). Conclusions. This study demonstrated that in CAD patients 18 months after CABG, there was an increase in the frequency of right ventricular systolic and diastolic dysfunction. We also established the initial clinical, echocardiographic parameters, and perioperative complications associated with the presence of these changes in the postoperative period. The clinical and prognostic significance of the presence of systolic and/or diastolic RV dysfunction in patients 18 months after CABG remains to be explored. |
format | Online Article Text |
id | pubmed-9318021 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-93180212022-07-27 Indicators of the Right Ventricle Systolic and Diastolic Function 18 Months after Coronary Bypass Surgery Sumin, Alexey N. Shcheglova, Anna V. Korok, Ekaterina V. Sergeeva, Tatjana Ju. J Clin Med Article Objective. Right ventricular (RV) dysfunction after coronary artery bypass grafting (CABG) is associated with increased mortality and morbidity. In previous studies, the parameters of RV systolic function were mainly assessed, while the dynamics of RV diastolic function after surgery was practically not studied. The aim of this study was to study the dynamics of indicators of systolic and diastolic RV function after CABG as well as to identify factors associated with their presence. Methods. The study included 160 patients who underwent CABG and 36 volunteers with no history of coronary artery disease (CAD) as a control group. Echocardiographic examination of patients was performed to assess systolic and diastolic RV dysfunction before surgery and 18 months after CABG. A level of s’t < 10 cm/sec or TAPSE < 16 mm was considered as a sign of existing RV systolic dysfunction. RV diastolic dysfunction was defined as an Et/At ratio < 0.8 or >2.1 and/or an Et/et’ ratio > 6. Results. In CAD patients 18 months after CABG, there was an increase in the frequency of the right ventricular systolic (from 7.5% to 30%, p < 0.001) and diastolic (from 41.8% to 57.5%, p < 0.001) dysfunction. An increase in TAPSE (p = 0.007), a decrease in e’t (p = 0.005), and the presence of RV systolic dysfunction before surgery (p = 0.023) was associated with a significant increase in the likelihood of detecting RV systolic dysfunction 18 months after CABG (χ(2)(3) = 17.4, p = 0.001). High values of At before surgery (p = 0.021) and old myocardial infarction (p = 0.023) were significantly associated with an increased likelihood of detection of RV diastolic dysfunction 18 months after CABG (χ(2)(2) = 10.78, p = 0.005). Conclusions. This study demonstrated that in CAD patients 18 months after CABG, there was an increase in the frequency of right ventricular systolic and diastolic dysfunction. We also established the initial clinical, echocardiographic parameters, and perioperative complications associated with the presence of these changes in the postoperative period. The clinical and prognostic significance of the presence of systolic and/or diastolic RV dysfunction in patients 18 months after CABG remains to be explored. MDPI 2022-07-10 /pmc/articles/PMC9318021/ /pubmed/35887758 http://dx.doi.org/10.3390/jcm11143994 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Sumin, Alexey N. Shcheglova, Anna V. Korok, Ekaterina V. Sergeeva, Tatjana Ju. Indicators of the Right Ventricle Systolic and Diastolic Function 18 Months after Coronary Bypass Surgery |
title | Indicators of the Right Ventricle Systolic and Diastolic Function 18 Months after Coronary Bypass Surgery |
title_full | Indicators of the Right Ventricle Systolic and Diastolic Function 18 Months after Coronary Bypass Surgery |
title_fullStr | Indicators of the Right Ventricle Systolic and Diastolic Function 18 Months after Coronary Bypass Surgery |
title_full_unstemmed | Indicators of the Right Ventricle Systolic and Diastolic Function 18 Months after Coronary Bypass Surgery |
title_short | Indicators of the Right Ventricle Systolic and Diastolic Function 18 Months after Coronary Bypass Surgery |
title_sort | indicators of the right ventricle systolic and diastolic function 18 months after coronary bypass surgery |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9318021/ https://www.ncbi.nlm.nih.gov/pubmed/35887758 http://dx.doi.org/10.3390/jcm11143994 |
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