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A Mathematical Approach Using Strat-M(®) to Predict the Percutaneous Absorption of Chemicals under Finite Dose Conditions

Estimation of the percutaneous absorption is essential for the safety assessment of cosmetic and dermopharmaceutical products. Currently, an artificial membrane, Strat-M(®), has been focused on as the tool which could obtain the permeation parameters close to the skin-derived values. Nevertheless, f...

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Detalles Bibliográficos
Autores principales: Kunita, Ryoki, Nishijima, Takafumi, Todo, Hiroaki, Sugibayashi, Kenji, Sakaguchi, Hitoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9318111/
https://www.ncbi.nlm.nih.gov/pubmed/35890266
http://dx.doi.org/10.3390/pharmaceutics14071370