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A Mathematical Approach Using Strat-M(®) to Predict the Percutaneous Absorption of Chemicals under Finite Dose Conditions
Estimation of the percutaneous absorption is essential for the safety assessment of cosmetic and dermopharmaceutical products. Currently, an artificial membrane, Strat-M(®), has been focused on as the tool which could obtain the permeation parameters close to the skin-derived values. Nevertheless, f...
Autores principales: | Kunita, Ryoki, Nishijima, Takafumi, Todo, Hiroaki, Sugibayashi, Kenji, Sakaguchi, Hitoshi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9318111/ https://www.ncbi.nlm.nih.gov/pubmed/35890266 http://dx.doi.org/10.3390/pharmaceutics14071370 |
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