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In Vivo Bio-Activation of JWH-175 to JWH-018: Pharmacodynamic and Pharmacokinetic Studies in Mice

3-(1-Naphthalenylmethyl)-1-pentyl-1H-indole (JWH-175) is a synthetic cannabinoid illegally marketed for its psychoactive cannabis-like effects. This study aimed to investigate and compare in vitro and in vivo pharmacodynamic activity of JWH-175 with that of 1-naphthalenyl (1-pentyl-1H-indol-3-yl)-me...

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Detalles Bibliográficos
Autores principales: Tirri, Micaela, Arfè, Raffaella, Bilel, Sabrine, Corli, Giorgia, Marchetti, Beatrice, Fantinati, Anna, Vincenzi, Fabrizio, De-Giorgio, Fabio, Camuto, Cristian, Mazzarino, Monica, Barbieri, Mario, Gaudio, Rosa Maria, Varani, Katia, Borea, Pier Andrea, Botrè, Francesco, Marti, Matteo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9318133/
https://www.ncbi.nlm.nih.gov/pubmed/35887377
http://dx.doi.org/10.3390/ijms23148030