Design, synthesis, biological evaluation and molecular docking studies of novel pleuromutilin derivatives containing nitrogen heterocycle and alkylamine groups

A series of pleuromutilin derivatives containing alkylamine and nitrogen heterocycle groups were designed and synthesised under mild conditions. The in vitro antibacterial activity of these semisynthetic derivatives against four strains of Staphylococcus aureus (MRSA ATCC 43300, S.aureus ATCC 29213,...

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Detalles Bibliográficos
Autores principales: Wang, Qi, Liu, Jie, Zhou, Zi-Dan, Zhou, Ke-Xin, Li, Fei, Zhang, Qi-Wen, Wang, Shou-Kai, Wang, Wei, Jin, Zhen, Tang, You-Zhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9318235/
https://www.ncbi.nlm.nih.gov/pubmed/35875944
http://dx.doi.org/10.1080/14756366.2022.2104267

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