Cargando…

Postacute Laryngeal Injuries and Dysfunctions in COVID-19 Patients: A Scoping Review

Objective: To investigate post-acute laryngeal injuries and dysfunctions (PLID) in coronavirus disease 2019 (COVID-19) patients. Methods: Three independent investigators performed a systematic review of the literature studying PLID in patients with a history of COVID-19. The review was performed acc...

Descripción completa

Detalles Bibliográficos
Autores principales: Lechien, Jérôme R., Hans, Stéphane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9318309/
https://www.ncbi.nlm.nih.gov/pubmed/35887754
http://dx.doi.org/10.3390/jcm11143989
_version_ 1784755259482046464
author Lechien, Jérôme R.
Hans, Stéphane
author_facet Lechien, Jérôme R.
Hans, Stéphane
author_sort Lechien, Jérôme R.
collection PubMed
description Objective: To investigate post-acute laryngeal injuries and dysfunctions (PLID) in coronavirus disease 2019 (COVID-19) patients. Methods: Three independent investigators performed a systematic review of the literature studying PLID in patients with a history of COVID-19. The review was performed according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses Statement. Epidemiological, clinical, hospitalization features, laryngeal diseases, and voice outcomes were extracted from the included papers. Results: Eight papers met our inclusion criteria (393 patients) corresponding to five uncontrolled prospective and three retrospective studies. The most prevalent PLID were vocal fold dysmotility (65%), vocal fold edema (35%), muscle tension dysphonia (21%), and laryngopharyngeal reflux (24%). Posterior glottic stenosis (12%), granuloma (14%), and posterior glottic diastasis (12%) were the most common injuries. Most patients with PLID were obese and had a history of intensive care unit hospitalization, and orotracheal intubation. The delay between the discharge and the laryngology office consultation ranged from 51 to 122 days. The mean duration of intubation ranged from 10 to 34 days. Seventy-eight (49%) intubated patients were in the prone position. The proportion of patients requiring surgical treatment ranged from 39% to 70% (mean = 48%). There was an important heterogeneity between studies about inclusion, exclusion criteria, and outcomes. Conclusions: COVID-19 appeared to be associated with PLID, especially in patients with a history of intubation. However, future controlled studies are needed to evaluate if intubated COVID-19 patients reported more frequently PLID than patients who were intubated for other conditions.
format Online
Article
Text
id pubmed-9318309
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-93183092022-07-27 Postacute Laryngeal Injuries and Dysfunctions in COVID-19 Patients: A Scoping Review Lechien, Jérôme R. Hans, Stéphane J Clin Med Review Objective: To investigate post-acute laryngeal injuries and dysfunctions (PLID) in coronavirus disease 2019 (COVID-19) patients. Methods: Three independent investigators performed a systematic review of the literature studying PLID in patients with a history of COVID-19. The review was performed according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses Statement. Epidemiological, clinical, hospitalization features, laryngeal diseases, and voice outcomes were extracted from the included papers. Results: Eight papers met our inclusion criteria (393 patients) corresponding to five uncontrolled prospective and three retrospective studies. The most prevalent PLID were vocal fold dysmotility (65%), vocal fold edema (35%), muscle tension dysphonia (21%), and laryngopharyngeal reflux (24%). Posterior glottic stenosis (12%), granuloma (14%), and posterior glottic diastasis (12%) were the most common injuries. Most patients with PLID were obese and had a history of intensive care unit hospitalization, and orotracheal intubation. The delay between the discharge and the laryngology office consultation ranged from 51 to 122 days. The mean duration of intubation ranged from 10 to 34 days. Seventy-eight (49%) intubated patients were in the prone position. The proportion of patients requiring surgical treatment ranged from 39% to 70% (mean = 48%). There was an important heterogeneity between studies about inclusion, exclusion criteria, and outcomes. Conclusions: COVID-19 appeared to be associated with PLID, especially in patients with a history of intubation. However, future controlled studies are needed to evaluate if intubated COVID-19 patients reported more frequently PLID than patients who were intubated for other conditions. MDPI 2022-07-09 /pmc/articles/PMC9318309/ /pubmed/35887754 http://dx.doi.org/10.3390/jcm11143989 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Lechien, Jérôme R.
Hans, Stéphane
Postacute Laryngeal Injuries and Dysfunctions in COVID-19 Patients: A Scoping Review
title Postacute Laryngeal Injuries and Dysfunctions in COVID-19 Patients: A Scoping Review
title_full Postacute Laryngeal Injuries and Dysfunctions in COVID-19 Patients: A Scoping Review
title_fullStr Postacute Laryngeal Injuries and Dysfunctions in COVID-19 Patients: A Scoping Review
title_full_unstemmed Postacute Laryngeal Injuries and Dysfunctions in COVID-19 Patients: A Scoping Review
title_short Postacute Laryngeal Injuries and Dysfunctions in COVID-19 Patients: A Scoping Review
title_sort postacute laryngeal injuries and dysfunctions in covid-19 patients: a scoping review
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9318309/
https://www.ncbi.nlm.nih.gov/pubmed/35887754
http://dx.doi.org/10.3390/jcm11143989
work_keys_str_mv AT lechienjeromer postacutelaryngealinjuriesanddysfunctionsincovid19patientsascopingreview
AT hansstephane postacutelaryngealinjuriesanddysfunctionsincovid19patientsascopingreview