Tumor-Derived Membrane Vesicles: A Promising Tool for Personalized Immunotherapy

Tumor-derived membrane vesicles (TDMVs) are non-invasive, chemotactic, easily obtained characteristics and contain various tumor-borne substances, such as nucleic acid and proteins. The unique properties of tumor cells and membranes make them widely used in drug loading, membrane fusion and vaccines...

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Detalles Bibliográficos
Autores principales: Xu, Jiabin, Cao, Wenqiang, Wang, Penglai, Liu, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9318328/
https://www.ncbi.nlm.nih.gov/pubmed/35890175
http://dx.doi.org/10.3390/ph15070876
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author Xu, Jiabin
Cao, Wenqiang
Wang, Penglai
Liu, Hong
author_facet Xu, Jiabin
Cao, Wenqiang
Wang, Penglai
Liu, Hong
author_sort Xu, Jiabin
collection PubMed
description Tumor-derived membrane vesicles (TDMVs) are non-invasive, chemotactic, easily obtained characteristics and contain various tumor-borne substances, such as nucleic acid and proteins. The unique properties of tumor cells and membranes make them widely used in drug loading, membrane fusion and vaccines. In particular, personalized vectors prepared using the editable properties of cells can help in the design of personalized vaccines. This review focuses on recent research on TDMV technology and its application in personalized immunotherapy. We elucidate the strengths and challenges of TDMVs to promote their application from theory to clinical practice.
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spelling pubmed-93183282022-07-27 Tumor-Derived Membrane Vesicles: A Promising Tool for Personalized Immunotherapy Xu, Jiabin Cao, Wenqiang Wang, Penglai Liu, Hong Pharmaceuticals (Basel) Review Tumor-derived membrane vesicles (TDMVs) are non-invasive, chemotactic, easily obtained characteristics and contain various tumor-borne substances, such as nucleic acid and proteins. The unique properties of tumor cells and membranes make them widely used in drug loading, membrane fusion and vaccines. In particular, personalized vectors prepared using the editable properties of cells can help in the design of personalized vaccines. This review focuses on recent research on TDMV technology and its application in personalized immunotherapy. We elucidate the strengths and challenges of TDMVs to promote their application from theory to clinical practice. MDPI 2022-07-16 /pmc/articles/PMC9318328/ /pubmed/35890175 http://dx.doi.org/10.3390/ph15070876 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Xu, Jiabin
Cao, Wenqiang
Wang, Penglai
Liu, Hong
Tumor-Derived Membrane Vesicles: A Promising Tool for Personalized Immunotherapy
title Tumor-Derived Membrane Vesicles: A Promising Tool for Personalized Immunotherapy
title_full Tumor-Derived Membrane Vesicles: A Promising Tool for Personalized Immunotherapy
title_fullStr Tumor-Derived Membrane Vesicles: A Promising Tool for Personalized Immunotherapy
title_full_unstemmed Tumor-Derived Membrane Vesicles: A Promising Tool for Personalized Immunotherapy
title_short Tumor-Derived Membrane Vesicles: A Promising Tool for Personalized Immunotherapy
title_sort tumor-derived membrane vesicles: a promising tool for personalized immunotherapy
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9318328/
https://www.ncbi.nlm.nih.gov/pubmed/35890175
http://dx.doi.org/10.3390/ph15070876
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