Using Dual Toll-like Receptor Agonism to Drive Th1-Biased Response in a Squalene- and α-Tocopherol-Containing Emulsion for a More Effective SARS-CoV-2 Vaccine

A diversity of vaccines is necessary to reduce the mortality and morbidity of SARS-CoV-2. Vaccines must be efficacious, easy to manufacture, and stable within the existing cold chain to improve their availability around the world. Recombinant protein subunit vaccines adjuvanted with squalene-based e...

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Detalles Bibliográficos
Autores principales: Short, Kristopher K., Lathrop, Stephanie K., Davison, Clara J., Partlow, Haley A., Kaiser, Johnathan A., Tee, Rebekah D., Lorentz, Elizabeth B., Evans, Jay T., Burkhart, David J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9318334/
https://www.ncbi.nlm.nih.gov/pubmed/35890352
http://dx.doi.org/10.3390/pharmaceutics14071455

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