IL-17 Cytokines and Chronic Lung Diseases

IL-17 cytokines are expressed by numerous cells (e.g., gamma delta (γδ) T, innate lymphoid (ILC), Th17, epithelial cells). They contribute to the elimination of bacteria through the induction of cytokines and chemokines which mediate the recruitment of inflammatory cells to the site of infection. Ho...

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Autores principales: Ritzmann, Felix, Lunding, Lars Peter, Bals, Robert, Wegmann, Michael, Beisswenger, Christoph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9318387/
https://www.ncbi.nlm.nih.gov/pubmed/35883573
http://dx.doi.org/10.3390/cells11142132
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author Ritzmann, Felix
Lunding, Lars Peter
Bals, Robert
Wegmann, Michael
Beisswenger, Christoph
author_facet Ritzmann, Felix
Lunding, Lars Peter
Bals, Robert
Wegmann, Michael
Beisswenger, Christoph
author_sort Ritzmann, Felix
collection PubMed
description IL-17 cytokines are expressed by numerous cells (e.g., gamma delta (γδ) T, innate lymphoid (ILC), Th17, epithelial cells). They contribute to the elimination of bacteria through the induction of cytokines and chemokines which mediate the recruitment of inflammatory cells to the site of infection. However, IL-17-driven inflammation also likely promotes the progression of chronic lung diseases, such as chronic obstructive pulmonary disease (COPD), lung cancer, cystic fibrosis, and asthma. In this review, we highlight the role of IL-17 cytokines in chronic lung diseases.
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spelling pubmed-93183872022-07-27 IL-17 Cytokines and Chronic Lung Diseases Ritzmann, Felix Lunding, Lars Peter Bals, Robert Wegmann, Michael Beisswenger, Christoph Cells Review IL-17 cytokines are expressed by numerous cells (e.g., gamma delta (γδ) T, innate lymphoid (ILC), Th17, epithelial cells). They contribute to the elimination of bacteria through the induction of cytokines and chemokines which mediate the recruitment of inflammatory cells to the site of infection. However, IL-17-driven inflammation also likely promotes the progression of chronic lung diseases, such as chronic obstructive pulmonary disease (COPD), lung cancer, cystic fibrosis, and asthma. In this review, we highlight the role of IL-17 cytokines in chronic lung diseases. MDPI 2022-07-06 /pmc/articles/PMC9318387/ /pubmed/35883573 http://dx.doi.org/10.3390/cells11142132 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Ritzmann, Felix
Lunding, Lars Peter
Bals, Robert
Wegmann, Michael
Beisswenger, Christoph
IL-17 Cytokines and Chronic Lung Diseases
title IL-17 Cytokines and Chronic Lung Diseases
title_full IL-17 Cytokines and Chronic Lung Diseases
title_fullStr IL-17 Cytokines and Chronic Lung Diseases
title_full_unstemmed IL-17 Cytokines and Chronic Lung Diseases
title_short IL-17 Cytokines and Chronic Lung Diseases
title_sort il-17 cytokines and chronic lung diseases
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9318387/
https://www.ncbi.nlm.nih.gov/pubmed/35883573
http://dx.doi.org/10.3390/cells11142132
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AT balsrobert il17cytokinesandchroniclungdiseases
AT wegmannmichael il17cytokinesandchroniclungdiseases
AT beisswengerchristoph il17cytokinesandchroniclungdiseases

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