Edaravone Modulates Neuronal GPX4/ACSL4/5-LOX to Promote Recovery After Spinal Cord Injury

The FDA-approved drug edaravone has a neuroprotective effect on spinal cord injury (SCI) and many other central nervous system diseases. However, its molecular mechanism remains unclear. Since edaravone is a lipid peroxidation scavenger, we hypothesize that edaravone exerts its neuroprotective effec...

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Detalles Bibliográficos
Autores principales: Pang, Yilin, Liu, Xinjie, Wang, Xu, Shi, Xuelian, Ma, Lei, Zhang, Yan, Zhou, Tiangang, Zhao, Chenxi, Zhang, Xu, Fan, Baoyou, Hao, Jian, Li, Wenxiang, Zhao, Xiaoqing, Zhang, Rong, Zhou, Songlin, Kong, Xiaohong, Feng, Shiqing, Yao, Xue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9318422/
https://www.ncbi.nlm.nih.gov/pubmed/35903552
http://dx.doi.org/10.3389/fcell.2022.849854

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