Gene Expression and Protein Abundance of Nuclear Receptors in Human Intestine and Liver: A New Application for Mass Spectrometry-Based Targeted Proteomics

Background: Unwanted drug-drug interactions (DDIs), as caused by the upregulation of clinically relevant drug metabolizing enzymes and transporter proteins in intestine and liver, have the potential to threaten the therapeutic efficacy and safety of drugs. The molecular mechanism of this undesired b...

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Detalles Bibliográficos
Autores principales: Wenzel, Christoph, Gödtke, Lisa, Reichstein, Anne, Keiser, Markus, Busch, Diana, Drozdzik, Marek, Oswald, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9318449/
https://www.ncbi.nlm.nih.gov/pubmed/35889510
http://dx.doi.org/10.3390/molecules27144629

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