Management of Type 2 Diabetes Mellitus in Elderly Patients with Frailty and/or Sarcopenia

The life expectancy of the population is increasing worldwide due to improvements in the prevention, diagnosis, and treatment of diseases. This favors a higher prevalence of type 2 diabetes mellitus (T2DM) in the elderly. Sarcopenia and frailty are also frequently present in aging. These three entit...

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Detalles Bibliográficos
Autores principales: Sanz-Cánovas, Jaime, López-Sampalo, Almudena, Cobos-Palacios, Lidia, Ricci, Michele, Hernández-Negrín, Halbert, Mancebo-Sevilla, Juan José, Álvarez-Recio, Elena, López-Carmona, María Dolores, Pérez-Belmonte, Luis Miguel, Gómez-Huelgas, Ricardo, Bernal-López, Maria Rosa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9318510/
https://www.ncbi.nlm.nih.gov/pubmed/35886528
http://dx.doi.org/10.3390/ijerph19148677
Descripción
Sumario:The life expectancy of the population is increasing worldwide due to improvements in the prevention, diagnosis, and treatment of diseases. This favors a higher prevalence of type 2 diabetes mellitus (T2DM) in the elderly. Sarcopenia and frailty are also frequently present in aging. These three entities share common mechanisms such as insulin resistance, chronic inflammation, and mitochondrial dysfunction. The coexistence of these situations worsens the prognosis of elderly patients. In this paper, we review the main measures for the prevention and management of sarcopenia and/or frailty in elderly patients with T2DM.

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