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Management of Type 2 Diabetes Mellitus in Elderly Patients with Frailty and/or Sarcopenia

The life expectancy of the population is increasing worldwide due to improvements in the prevention, diagnosis, and treatment of diseases. This favors a higher prevalence of type 2 diabetes mellitus (T2DM) in the elderly. Sarcopenia and frailty are also frequently present in aging. These three entit...

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Autores principales: Sanz-Cánovas, Jaime, López-Sampalo, Almudena, Cobos-Palacios, Lidia, Ricci, Michele, Hernández-Negrín, Halbert, Mancebo-Sevilla, Juan José, Álvarez-Recio, Elena, López-Carmona, María Dolores, Pérez-Belmonte, Luis Miguel, Gómez-Huelgas, Ricardo, Bernal-López, Maria Rosa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9318510/
https://www.ncbi.nlm.nih.gov/pubmed/35886528
http://dx.doi.org/10.3390/ijerph19148677
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author Sanz-Cánovas, Jaime
López-Sampalo, Almudena
Cobos-Palacios, Lidia
Ricci, Michele
Hernández-Negrín, Halbert
Mancebo-Sevilla, Juan José
Álvarez-Recio, Elena
López-Carmona, María Dolores
Pérez-Belmonte, Luis Miguel
Gómez-Huelgas, Ricardo
Bernal-López, Maria Rosa
author_facet Sanz-Cánovas, Jaime
López-Sampalo, Almudena
Cobos-Palacios, Lidia
Ricci, Michele
Hernández-Negrín, Halbert
Mancebo-Sevilla, Juan José
Álvarez-Recio, Elena
López-Carmona, María Dolores
Pérez-Belmonte, Luis Miguel
Gómez-Huelgas, Ricardo
Bernal-López, Maria Rosa
author_sort Sanz-Cánovas, Jaime
collection PubMed
description The life expectancy of the population is increasing worldwide due to improvements in the prevention, diagnosis, and treatment of diseases. This favors a higher prevalence of type 2 diabetes mellitus (T2DM) in the elderly. Sarcopenia and frailty are also frequently present in aging. These three entities share common mechanisms such as insulin resistance, chronic inflammation, and mitochondrial dysfunction. The coexistence of these situations worsens the prognosis of elderly patients. In this paper, we review the main measures for the prevention and management of sarcopenia and/or frailty in elderly patients with T2DM.
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spelling pubmed-93185102022-07-27 Management of Type 2 Diabetes Mellitus in Elderly Patients with Frailty and/or Sarcopenia Sanz-Cánovas, Jaime López-Sampalo, Almudena Cobos-Palacios, Lidia Ricci, Michele Hernández-Negrín, Halbert Mancebo-Sevilla, Juan José Álvarez-Recio, Elena López-Carmona, María Dolores Pérez-Belmonte, Luis Miguel Gómez-Huelgas, Ricardo Bernal-López, Maria Rosa Int J Environ Res Public Health Review The life expectancy of the population is increasing worldwide due to improvements in the prevention, diagnosis, and treatment of diseases. This favors a higher prevalence of type 2 diabetes mellitus (T2DM) in the elderly. Sarcopenia and frailty are also frequently present in aging. These three entities share common mechanisms such as insulin resistance, chronic inflammation, and mitochondrial dysfunction. The coexistence of these situations worsens the prognosis of elderly patients. In this paper, we review the main measures for the prevention and management of sarcopenia and/or frailty in elderly patients with T2DM. MDPI 2022-07-16 /pmc/articles/PMC9318510/ /pubmed/35886528 http://dx.doi.org/10.3390/ijerph19148677 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Sanz-Cánovas, Jaime
López-Sampalo, Almudena
Cobos-Palacios, Lidia
Ricci, Michele
Hernández-Negrín, Halbert
Mancebo-Sevilla, Juan José
Álvarez-Recio, Elena
López-Carmona, María Dolores
Pérez-Belmonte, Luis Miguel
Gómez-Huelgas, Ricardo
Bernal-López, Maria Rosa
Management of Type 2 Diabetes Mellitus in Elderly Patients with Frailty and/or Sarcopenia
title Management of Type 2 Diabetes Mellitus in Elderly Patients with Frailty and/or Sarcopenia
title_full Management of Type 2 Diabetes Mellitus in Elderly Patients with Frailty and/or Sarcopenia
title_fullStr Management of Type 2 Diabetes Mellitus in Elderly Patients with Frailty and/or Sarcopenia
title_full_unstemmed Management of Type 2 Diabetes Mellitus in Elderly Patients with Frailty and/or Sarcopenia
title_short Management of Type 2 Diabetes Mellitus in Elderly Patients with Frailty and/or Sarcopenia
title_sort management of type 2 diabetes mellitus in elderly patients with frailty and/or sarcopenia
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9318510/
https://www.ncbi.nlm.nih.gov/pubmed/35886528
http://dx.doi.org/10.3390/ijerph19148677
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