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The Pro-Inflammatory Deletion Allele of the NF-κB1 Polymorphism Is Characterized by a Depletion of Subunit p50 in Sepsis

The functionally important NF-κB1 promoter polymorphism (−94ins/delATTG) significantly shapes inflammation and impacts the outcome of sepsis. However, exploratory studies elucidating the molecular link of this genotype-dependent pattern are lacking. Accordingly, we analyzed lipopolysaccharide-stimul...

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Detalles Bibliográficos
Autores principales:	Marko, Britta, Heurich, Paulina, Thon, Patrick, Zimmer, Frieda, Bergmann, Lars, Nowak, Hartmuth, Rump, Katharina, Koos, Björn, Adamzik, Michael, Unterberg, Matthias, Rahmel, Tim
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9318670/ https://www.ncbi.nlm.nih.gov/pubmed/35886907 http://dx.doi.org/10.3390/ijms23147559

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