Identification of NAPRT Inhibitors with Anti-Cancer Properties by In Silico Drug Discovery

Depriving cancer cells of sufficient NAD levels, mainly through interfering with their NAD-producing capacity, has been conceived as a promising anti-cancer strategy. Numerous inhibitors of the NAD-producing enzyme, nicotinamide phosphoribosyltransferase (NAMPT), have been developed over the past tw...

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Detalles Bibliográficos
Autores principales: Ghanem, Moustafa S., Caffa, Irene, Del Rio, Alberto, Franco, Jorge, Parenti, Marco Daniele, Monacelli, Fiammetta, Cea, Michele, Khalifa, Amr, Nahimana, Aimable, Duchosal, Michel A., Ravera, Silvia, Bertola, Nadia, Bruzzone, Santina, Nencioni, Alessio, Piacente, Francesco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9318686/
https://www.ncbi.nlm.nih.gov/pubmed/35890147
http://dx.doi.org/10.3390/ph15070848

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