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Dynamic Features of Chromosomal Instability during Culture of Induced Pluripotent Stem Cells

Induced pluripotent stem cells (iPSCs) hold great potential for regenerative medicine. By reprogramming a patient′s own cells, immunological rejection can be avoided during transplantation. For expansion and gene editing, iPSCs are grown in artificial culture for extended times. Culture affords pote...

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Detalles Bibliográficos
Autores principales: DuBose, Casey O., Daum, John R., Sansam, Christopher L., Gorbsky, Gary J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9318709/
https://www.ncbi.nlm.nih.gov/pubmed/35885940
http://dx.doi.org/10.3390/genes13071157